Is ergothioneine a ‘longevity vitamin’ limited in the American diet?

There is mounting evidence for the potential for the natural dietary antioxidant and anti-inflammatory amino acid l-Ergothioneine (ERGO) to prevent or mitigate chronic diseases of aging. This has led to the suggestion that it could be considered a ‘longevity vitamin.’ ERGO is produced in nature only...

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Main Authors: Robert B. Beelman, Michael D. Kalaras, Allen T. Phillips, John P. Richie
Format: Article
Language:English
Published: Cambridge University Press 2020-01-01
Series:Journal of Nutritional Science
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S2048679020000440/type/journal_article
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author Robert B. Beelman
Michael D. Kalaras
Allen T. Phillips
John P. Richie
author_facet Robert B. Beelman
Michael D. Kalaras
Allen T. Phillips
John P. Richie
author_sort Robert B. Beelman
collection DOAJ
description There is mounting evidence for the potential for the natural dietary antioxidant and anti-inflammatory amino acid l-Ergothioneine (ERGO) to prevent or mitigate chronic diseases of aging. This has led to the suggestion that it could be considered a ‘longevity vitamin.’ ERGO is produced in nature only by certain fungi and a few other microbes. Mushrooms are, by far, the leading dietary source of ERGO, but it is found in small amounts throughout the food chain, most likely due to soil-borne fungi passing it on to plants. Because some common agricultural practices can disrupt beneficial fungus–plant root relationships, ERGO levels in foods grown under those conditions could be compromised. Thus, research is needed to further analyse the role agricultural practices play in the availability of ERGO in the human diet and its potential to improve our long-term health.
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spelling doaj.art-ca9365cfdbd74bf8a61abdd12e40cf062023-03-09T12:39:11ZengCambridge University PressJournal of Nutritional Science2048-67902020-01-01910.1017/jns.2020.44Is ergothioneine a ‘longevity vitamin’ limited in the American diet?Robert B. Beelman0Michael D. Kalaras1Allen T. Phillips2John P. Richie3Department of Food Science, College of Agricultural Sciences, Center for Plant and Mushroom Foods for Health, Penn State University, 202 Rodney A. Erickson Food Science Building, University Park, PA 16802, USADepartment of Food Science, College of Agricultural Sciences, Center for Plant and Mushroom Foods for Health, Penn State University, 202 Rodney A. Erickson Food Science Building, University Park, PA 16802, USADepartment of Biochemistry and Molecular Biology, Eberly College of Science, Center for Plant and Mushroom Foods for Health, Penn State University, 203A South Frear Building, University Park, PA 16802, USADepartment Public Health Science, College of Medicine, Center for Plant and Mushroom Foods for Health, Penn State University, 500 University Dr., Hershey, PA 17033, USAThere is mounting evidence for the potential for the natural dietary antioxidant and anti-inflammatory amino acid l-Ergothioneine (ERGO) to prevent or mitigate chronic diseases of aging. This has led to the suggestion that it could be considered a ‘longevity vitamin.’ ERGO is produced in nature only by certain fungi and a few other microbes. Mushrooms are, by far, the leading dietary source of ERGO, but it is found in small amounts throughout the food chain, most likely due to soil-borne fungi passing it on to plants. Because some common agricultural practices can disrupt beneficial fungus–plant root relationships, ERGO levels in foods grown under those conditions could be compromised. Thus, research is needed to further analyse the role agricultural practices play in the availability of ERGO in the human diet and its potential to improve our long-term health.https://www.cambridge.org/core/product/identifier/S2048679020000440/type/journal_articleErgothioneineLongevity vitaminFungiRegenerative agricultureAntioxidant
spellingShingle Robert B. Beelman
Michael D. Kalaras
Allen T. Phillips
John P. Richie
Is ergothioneine a ‘longevity vitamin’ limited in the American diet?
Journal of Nutritional Science
Ergothioneine
Longevity vitamin
Fungi
Regenerative agriculture
Antioxidant
title Is ergothioneine a ‘longevity vitamin’ limited in the American diet?
title_full Is ergothioneine a ‘longevity vitamin’ limited in the American diet?
title_fullStr Is ergothioneine a ‘longevity vitamin’ limited in the American diet?
title_full_unstemmed Is ergothioneine a ‘longevity vitamin’ limited in the American diet?
title_short Is ergothioneine a ‘longevity vitamin’ limited in the American diet?
title_sort is ergothioneine a longevity vitamin limited in the american diet
topic Ergothioneine
Longevity vitamin
Fungi
Regenerative agriculture
Antioxidant
url https://www.cambridge.org/core/product/identifier/S2048679020000440/type/journal_article
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