Primary leiomyosarcoma of the broad ligament: A case report with review of literature

Primary leiomyosarcoma of the broad ligament is a very rare and highly malignant tumour with very few cases being reported in literature. They have an aggressive course and occur usually in postmenopausal women. We herein report a rare case of primary leiomyosarcoma of the broad ligament which was d...

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Main Authors: Devika Gupta, Giriraj Singh, Pooja Gupta, Satish Mendonca, Kamlesh Kumar Singh
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Human Pathology: Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221433001420112X
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author Devika Gupta
Giriraj Singh
Pooja Gupta
Satish Mendonca
Kamlesh Kumar Singh
author_facet Devika Gupta
Giriraj Singh
Pooja Gupta
Satish Mendonca
Kamlesh Kumar Singh
author_sort Devika Gupta
collection DOAJ
description Primary leiomyosarcoma of the broad ligament is a very rare and highly malignant tumour with very few cases being reported in literature. They have an aggressive course and occur usually in postmenopausal women. We herein report a rare case of primary leiomyosarcoma of the broad ligament which was diagnosed based on imaging, the classical histomorphological and immunohistochemistry features and subsequently treated by complete surgical resection. Primary leiomyosarcoma of the broad ligament is a rapidly progressive and highly malignant gynaecological tumour. It requires complete surgery (hysterectomy with bilateral salpingoophorectomy) for all cases. Adjuvant chemotherapy or radiotherapy is used in selected cases. Low to intermediate grade tumours with no evidence of metastasis are treated surgically only, with advice for a close follow-up.
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spelling doaj.art-ca96d600c03e41b992dcc53316b28aaf2022-12-22T03:30:50ZengElsevierHuman Pathology: Case Reports2214-33002015-09-0123596210.1016/j.ehpc.2015.02.005Primary leiomyosarcoma of the broad ligament: A case report with review of literatureDevika Gupta0Giriraj Singh1Pooja Gupta2Satish Mendonca3Kamlesh Kumar Singh4Armed Forces Medical College, Department Of Pathology and Laboratory Science, Command Hospital, Pune, 411040, IndiaArmed Forces Medical College, Department of Radiodiagnosis and Imaging, Command Hospital, Pune, 411040, IndiaArmed Forces Medical College, Department of Radiodiagnosis and Imaging, Command Hospital, Pune, 411040, IndiaArmed Forces Medical College, Department Of Medicine, Command Hospital, Pune, 411040, IndiaArmed Forces Medical College, Department Of Pathology and Laboratory Science, Command Hospital, Pune, 411040, IndiaPrimary leiomyosarcoma of the broad ligament is a very rare and highly malignant tumour with very few cases being reported in literature. They have an aggressive course and occur usually in postmenopausal women. We herein report a rare case of primary leiomyosarcoma of the broad ligament which was diagnosed based on imaging, the classical histomorphological and immunohistochemistry features and subsequently treated by complete surgical resection. Primary leiomyosarcoma of the broad ligament is a rapidly progressive and highly malignant gynaecological tumour. It requires complete surgery (hysterectomy with bilateral salpingoophorectomy) for all cases. Adjuvant chemotherapy or radiotherapy is used in selected cases. Low to intermediate grade tumours with no evidence of metastasis are treated surgically only, with advice for a close follow-up.http://www.sciencedirect.com/science/article/pii/S221433001420112XLeiomyosarcomaBroad ligamentUterus
spellingShingle Devika Gupta
Giriraj Singh
Pooja Gupta
Satish Mendonca
Kamlesh Kumar Singh
Primary leiomyosarcoma of the broad ligament: A case report with review of literature
Human Pathology: Case Reports
Leiomyosarcoma
Broad ligament
Uterus
title Primary leiomyosarcoma of the broad ligament: A case report with review of literature
title_full Primary leiomyosarcoma of the broad ligament: A case report with review of literature
title_fullStr Primary leiomyosarcoma of the broad ligament: A case report with review of literature
title_full_unstemmed Primary leiomyosarcoma of the broad ligament: A case report with review of literature
title_short Primary leiomyosarcoma of the broad ligament: A case report with review of literature
title_sort primary leiomyosarcoma of the broad ligament a case report with review of literature
topic Leiomyosarcoma
Broad ligament
Uterus
url http://www.sciencedirect.com/science/article/pii/S221433001420112X
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