Drivers of and Barriers to COVID-19 Vaccine Booster Dose Acceptance in Indonesia
Obtaining a booster dose of coronavirus disease 2019 (COVID-19) vaccine is required to maintain the protective level of neutralizing antibodies and therefore herd immunity in the community, and the success of booster dose programs depends on public acceptance. The aim of this study was to determine...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Vaccines |
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| Online Access: | https://www.mdpi.com/2076-393X/10/12/1981 |
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| author | Harapan Harapan Raisha Fathima Hendrix Indra Kusuma Samsul Anwar Widhy Yudistira Nalapraya Adityo Wibowo Ketut Dewi Kumara Wati Ayunda Medina Anna Hanifa Defrita Yesi Astri Arie Prasetyowati Nurfarahin Nurfarahin Afriyani Khusna Setya Oktariana Sarifuddin Anwar Milza Oka Yussar Siti Khotimah Bahagia Willibrordus Maria Nainggolan Putri Rizki Amalia Badri Raden Argarini Wira Winardi Rosaria Indah Malik Sallam Yogambigai Rajamoorthy Abram L. Wagner Mudatsir Mudatsir |
| author_facet | Harapan Harapan Raisha Fathima Hendrix Indra Kusuma Samsul Anwar Widhy Yudistira Nalapraya Adityo Wibowo Ketut Dewi Kumara Wati Ayunda Medina Anna Hanifa Defrita Yesi Astri Arie Prasetyowati Nurfarahin Nurfarahin Afriyani Khusna Setya Oktariana Sarifuddin Anwar Milza Oka Yussar Siti Khotimah Bahagia Willibrordus Maria Nainggolan Putri Rizki Amalia Badri Raden Argarini Wira Winardi Rosaria Indah Malik Sallam Yogambigai Rajamoorthy Abram L. Wagner Mudatsir Mudatsir |
| author_sort | Harapan Harapan |
| collection | DOAJ |
| description | Obtaining a booster dose of coronavirus disease 2019 (COVID-19) vaccine is required to maintain the protective level of neutralizing antibodies and therefore herd immunity in the community, and the success of booster dose programs depends on public acceptance. The aim of this study was to determine the acceptance of a booster dose of COVID-19 vaccine and its drivers and barriers in Indonesia. A cross-sectional survey was conducted in the provinces of Indonesia between 1 and 15 August 2022. Individuals who completed the primary series of the COVID-19 vaccine were asked about their acceptance of a booster dose. Those who refused the booster dose were questioned about their reasons. A logistic regression was used to determine the determinants associated with rejection of a booster dose of COVID-19 vaccine. A total of 2935 respondents were included in the final analysis. With no information on the efficacy and safety of the COVID-19 vaccine, 95% of respondents agreed to receive a booster dose if it were provided for free by the government. This acceptance was reduced to only 50.3% if the vaccine had a 75% efficacy with a 20% chance of side effects. The adjusted logistic regression analysis indicated that there were eight factors associated with the rejection of the booster dose: age, marital status, religion, occupation, type of the first two vaccines received, knowledge regarding the importance of the booster dose, belief that natural immunity is sufficient to prevent COVID-19 and disbelief in the effectiveness of the booster dose. In conclusion, the hesitancy toward booster doses in Indonesia is influenced by some intrinsic factors such as lack of knowledge on the benefits of the booster dose, worries regarding the unexpected side effects and concerns about the halal status of the provided vaccines and extrinsic determinants such as the effectiveness and safety of the vaccine. These findings suggest the need for more campaigns and promotions regarding the booster dose benefits to increase its acceptance. |
| first_indexed | 2024-03-09T15:46:08Z |
| format | Article |
| id | doaj.art-ca9802bb074f4729bb2160fdfa9213a2 |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-09T15:46:08Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-ca9802bb074f4729bb2160fdfa9213a22023-11-24T18:30:33ZengMDPI AGVaccines2076-393X2022-11-011012198110.3390/vaccines10121981Drivers of and Barriers to COVID-19 Vaccine Booster Dose Acceptance in IndonesiaHarapan Harapan0Raisha Fathima1Hendrix Indra Kusuma2Samsul Anwar3Widhy Yudistira Nalapraya4Adityo Wibowo5Ketut Dewi Kumara Wati6Ayunda Medina7Anna Hanifa Defrita8Yesi Astri9Arie Prasetyowati10Nurfarahin Nurfarahin11Afriyani Khusna12Setya Oktariana13Sarifuddin Anwar14Milza Oka Yussar15Siti Khotimah16Bahagia Willibrordus Maria Nainggolan17Putri Rizki Amalia Badri18Raden Argarini19Wira Winardi20Rosaria Indah21Malik Sallam22Yogambigai Rajamoorthy23Abram L. Wagner24Mudatsir Mudatsir25Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, IndonesiaMedical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, IndonesiaMedical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, IndonesiaDepartment of Statistics, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh 23111, IndonesiaDepartment of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Islam Bandung, Bandung 40116, IndonesiaDepartment of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Lampung, Bandar Lampung 35145, IndonesiaDepartment of Child Health, Faculty of Medicine, Universitas Udayana, Denpasar 80234, IndonesiaMedical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, IndonesiaFaculty of Medicine, Universitas Jambi, Jambi 36373, IndonesiaNeurology Department, Faculty of Medicine, Universitas Muhammadiyah Palembang, Palembang 30263, IndonesiaMungkid Community Health Center, Magelang 56512, IndonesiaMedical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, IndonesiaMedical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, IndonesiaMedical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, IndonesiaDepartment of Pulmonology and Respiratory Medicine, Faculty of Medicine, Tadulako University, Palu 94148, IndonesiaFaculty of Public Health, University Muhammadiyah Aceh, Banda Aceh 23245, IndonesiaBiochemistry Laboratory, Medical Faculty of Mulawarman University, Samarinda 75119, IndonesiaUndergraduate Program in Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan 20155, IndonesiaPublic Health Department, Faculty of Medicine, Universitas Muhammadiyah Palembang, Palembang 30263, IndonesiaDepartment of Medical Physiology and Biochemistry, Universitas Airlangga, Surabaya 60132, IndonesiaDepartment of Pulmonology and Respiratory Medicine, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, IndonesiaMedical Education Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, IndonesiaDepartment of Pathology, Microbiology and Forensic Medicine, School of Medicine, The University of Jordan, Amman 11942, JordanDepartment of Economics, Faculty of Accountancy and Management, Universiti Tunku Abdul Rahman, Kuala Lumpur 43200, MalaysiaDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USAMedical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, IndonesiaObtaining a booster dose of coronavirus disease 2019 (COVID-19) vaccine is required to maintain the protective level of neutralizing antibodies and therefore herd immunity in the community, and the success of booster dose programs depends on public acceptance. The aim of this study was to determine the acceptance of a booster dose of COVID-19 vaccine and its drivers and barriers in Indonesia. A cross-sectional survey was conducted in the provinces of Indonesia between 1 and 15 August 2022. Individuals who completed the primary series of the COVID-19 vaccine were asked about their acceptance of a booster dose. Those who refused the booster dose were questioned about their reasons. A logistic regression was used to determine the determinants associated with rejection of a booster dose of COVID-19 vaccine. A total of 2935 respondents were included in the final analysis. With no information on the efficacy and safety of the COVID-19 vaccine, 95% of respondents agreed to receive a booster dose if it were provided for free by the government. This acceptance was reduced to only 50.3% if the vaccine had a 75% efficacy with a 20% chance of side effects. The adjusted logistic regression analysis indicated that there were eight factors associated with the rejection of the booster dose: age, marital status, religion, occupation, type of the first two vaccines received, knowledge regarding the importance of the booster dose, belief that natural immunity is sufficient to prevent COVID-19 and disbelief in the effectiveness of the booster dose. In conclusion, the hesitancy toward booster doses in Indonesia is influenced by some intrinsic factors such as lack of knowledge on the benefits of the booster dose, worries regarding the unexpected side effects and concerns about the halal status of the provided vaccines and extrinsic determinants such as the effectiveness and safety of the vaccine. These findings suggest the need for more campaigns and promotions regarding the booster dose benefits to increase its acceptance.https://www.mdpi.com/2076-393X/10/12/1981booster dosevaccine acceptancevaccine reluctanceCOVID-19vaccine resistancevaccine rejection |
| spellingShingle | Harapan Harapan Raisha Fathima Hendrix Indra Kusuma Samsul Anwar Widhy Yudistira Nalapraya Adityo Wibowo Ketut Dewi Kumara Wati Ayunda Medina Anna Hanifa Defrita Yesi Astri Arie Prasetyowati Nurfarahin Nurfarahin Afriyani Khusna Setya Oktariana Sarifuddin Anwar Milza Oka Yussar Siti Khotimah Bahagia Willibrordus Maria Nainggolan Putri Rizki Amalia Badri Raden Argarini Wira Winardi Rosaria Indah Malik Sallam Yogambigai Rajamoorthy Abram L. Wagner Mudatsir Mudatsir Drivers of and Barriers to COVID-19 Vaccine Booster Dose Acceptance in Indonesia Vaccines booster dose vaccine acceptance vaccine reluctance COVID-19 vaccine resistance vaccine rejection |
| title | Drivers of and Barriers to COVID-19 Vaccine Booster Dose Acceptance in Indonesia |
| title_full | Drivers of and Barriers to COVID-19 Vaccine Booster Dose Acceptance in Indonesia |
| title_fullStr | Drivers of and Barriers to COVID-19 Vaccine Booster Dose Acceptance in Indonesia |
| title_full_unstemmed | Drivers of and Barriers to COVID-19 Vaccine Booster Dose Acceptance in Indonesia |
| title_short | Drivers of and Barriers to COVID-19 Vaccine Booster Dose Acceptance in Indonesia |
| title_sort | drivers of and barriers to covid 19 vaccine booster dose acceptance in indonesia |
| topic | booster dose vaccine acceptance vaccine reluctance COVID-19 vaccine resistance vaccine rejection |
| url | https://www.mdpi.com/2076-393X/10/12/1981 |
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