The Shift of Bacterial Sensitivity with Antibiotics in Acute Tonsillitis
Background: The infection of tonsil may occur primarily or secondarily as a result of upper respiratory tract infection, usually preceded by a viral infection. Bacterial tonsillitis is most commonly caused by Streptococcus pyogenes. Penicillin remains the treatment of choice for S. pyogenes tonsilli...
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| Format: | Article |
| Language: | English |
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Nobel Medical College Teaching Hospital
2021-06-01
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| Series: | Journal of Nobel Medical College |
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| Online Access: | https://www.nepjol.info/index.php/JoNMC/article/view/37807 |
| _version_ | 1818862480623927296 |
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| author | Brihaspati Sigdel |
| author_facet | Brihaspati Sigdel |
| author_sort | Brihaspati Sigdel |
| collection | DOAJ |
| description | Background: The infection of tonsil may occur primarily or secondarily as a result of upper respiratory tract infection, usually preceded by a viral infection. Bacterial tonsillitis is most commonly caused by Streptococcus pyogenes. Penicillin remains the treatment of choice for S. pyogenes tonsillitis. The present study aimed to identify the bacterial pathogen in acute tonsillitis and their sensitivity to antibiotics.
Material and Methods: This prospective study was conducted in the Department of Otolaryngology and Head & Neck Surgery and Department of Microbiology, Gandaki Medical College, Pokhara Nepal from January 2018 to January 2019. Ninety-six patients who presented with acute tonsillitis and admitted in the hospital were included in the study.
Results: The commonest age group of acute tonsillitis was found to be between 21-30 years. S. pyogenes was the commonest isolate 32(33.3%) followed by S. aureus 19(19.8%). Streptococcus pyogenes was sensitive to Ampicillin (65.6%) and Cloxacillin (68.7%) while the isolates were more sensitive to levofloxacin and doxycycline. Carbapenem were found to be most effective drugs for intravenous treatment.
Conclusion: The most common bacterial isolates were Streptococcus pyogenes. The sensitivity of organism shift from ampicillin group to fluroquinolones and tetracycline. Identification of bacterial isolates and their antibiotics sensitivity patterns could prevent resistance of bacteria to drugs and help in the proper management of acute tonsillitis. |
| first_indexed | 2024-12-19T10:00:32Z |
| format | Article |
| id | doaj.art-ca9962e5db8a4099b339328c3690b8d0 |
| institution | Directory Open Access Journal |
| issn | 2091-2331 2091-234X |
| language | English |
| last_indexed | 2024-12-19T10:00:32Z |
| publishDate | 2021-06-01 |
| publisher | Nobel Medical College Teaching Hospital |
| record_format | Article |
| series | Journal of Nobel Medical College |
| spelling | doaj.art-ca9962e5db8a4099b339328c3690b8d02022-12-21T20:26:39ZengNobel Medical College Teaching HospitalJournal of Nobel Medical College2091-23312091-234X2021-06-011013610.3126/jonmc.v10i1.3780737807The Shift of Bacterial Sensitivity with Antibiotics in Acute TonsillitisBrihaspati Sigdel0Department of Otolaryngology & Head and Neck Surgery, Gandaki Medical College, Pokhara, NepalBackground: The infection of tonsil may occur primarily or secondarily as a result of upper respiratory tract infection, usually preceded by a viral infection. Bacterial tonsillitis is most commonly caused by Streptococcus pyogenes. Penicillin remains the treatment of choice for S. pyogenes tonsillitis. The present study aimed to identify the bacterial pathogen in acute tonsillitis and their sensitivity to antibiotics. Material and Methods: This prospective study was conducted in the Department of Otolaryngology and Head & Neck Surgery and Department of Microbiology, Gandaki Medical College, Pokhara Nepal from January 2018 to January 2019. Ninety-six patients who presented with acute tonsillitis and admitted in the hospital were included in the study. Results: The commonest age group of acute tonsillitis was found to be between 21-30 years. S. pyogenes was the commonest isolate 32(33.3%) followed by S. aureus 19(19.8%). Streptococcus pyogenes was sensitive to Ampicillin (65.6%) and Cloxacillin (68.7%) while the isolates were more sensitive to levofloxacin and doxycycline. Carbapenem were found to be most effective drugs for intravenous treatment. Conclusion: The most common bacterial isolates were Streptococcus pyogenes. The sensitivity of organism shift from ampicillin group to fluroquinolones and tetracycline. Identification of bacterial isolates and their antibiotics sensitivity patterns could prevent resistance of bacteria to drugs and help in the proper management of acute tonsillitis.https://www.nepjol.info/index.php/JoNMC/article/view/37807bacteriologystreptococcus pyogenestonsillitis |
| spellingShingle | Brihaspati Sigdel The Shift of Bacterial Sensitivity with Antibiotics in Acute Tonsillitis Journal of Nobel Medical College bacteriology streptococcus pyogenes tonsillitis |
| title | The Shift of Bacterial Sensitivity with Antibiotics in Acute Tonsillitis |
| title_full | The Shift of Bacterial Sensitivity with Antibiotics in Acute Tonsillitis |
| title_fullStr | The Shift of Bacterial Sensitivity with Antibiotics in Acute Tonsillitis |
| title_full_unstemmed | The Shift of Bacterial Sensitivity with Antibiotics in Acute Tonsillitis |
| title_short | The Shift of Bacterial Sensitivity with Antibiotics in Acute Tonsillitis |
| title_sort | shift of bacterial sensitivity with antibiotics in acute tonsillitis |
| topic | bacteriology streptococcus pyogenes tonsillitis |
| url | https://www.nepjol.info/index.php/JoNMC/article/view/37807 |
| work_keys_str_mv | AT brihaspatisigdel theshiftofbacterialsensitivitywithantibioticsinacutetonsillitis AT brihaspatisigdel shiftofbacterialsensitivitywithantibioticsinacutetonsillitis |