Vascular Adhesion Protein 1 Mediates Gut Microbial Flagellin-Induced Inflammation, Leukocyte Infiltration, and Hepatic Steatosis

Vascular Adhesion Protein 1 Mediates Gut Microbial Flagellin-Induced Inflammation, Leukocyte Infiltration, and Hepatic Steatosis

Toll-like receptor 5 ligand, flagellin, and vascular adhesion protein 1 (VAP-1) are involved in non-alcoholic fatty liver disease. This study aimed to determine whether VAP-1 mediates flagellin-induced hepatic fat accumulation. The effects of flagellin on adipocyte VAP-1 expression were first studie...

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Bibliographic Details
Main Authors: Raine Toivonen, Sanja Vanhatalo, Maija Hollmén, Eveliina Munukka, Anniina Keskitalo, Sami Pietilä, Laura Elo, Pentti Huovinen, Sirpa Jalkanen, Satu Pekkala
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Sci
Subjects:
gut microbiota
liver
metabolism
inflammation
Online Access:https://www.mdpi.com/2413-4155/3/1/13

Internet

https://www.mdpi.com/2413-4155/3/1/13

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