Entomological characterization of Aedes mosquitoes and arbovirus detection in Ibagué, a Colombian city with co-circulation of Zika, dengue and chikungunya viruses
Abstract Background Dengue, Zika and chikungunya are arboviruses of significant public health importance that are transmitted by Aedes aegypti and Aedes albopictus mosquitoes. In Colombia, where dengue is hyperendemic, and where chikungunya and Zika were introduced in the last decade, more than half...
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| Format: | Article |
| Language: | English |
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BMC
2021-09-01
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| Series: | Parasites & Vectors |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13071-021-04908-x |
| _version_ | 1818728933513756672 |
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| author | María C. Carrasquilla Mario I. Ortiz Cielo León Silvia Rondón Manisha A. Kulkarni Benoit Talbot Beate Sander Heriberto Vásquez Juan M. Cordovez Camila González RADAM-LAC Research Team |
| author_facet | María C. Carrasquilla Mario I. Ortiz Cielo León Silvia Rondón Manisha A. Kulkarni Benoit Talbot Beate Sander Heriberto Vásquez Juan M. Cordovez Camila González RADAM-LAC Research Team |
| author_sort | María C. Carrasquilla |
| collection | DOAJ |
| description | Abstract Background Dengue, Zika and chikungunya are arboviruses of significant public health importance that are transmitted by Aedes aegypti and Aedes albopictus mosquitoes. In Colombia, where dengue is hyperendemic, and where chikungunya and Zika were introduced in the last decade, more than half of the population lives in areas at risk. The objective of this study was to characterize Aedes spp. vectors and study their natural infection with dengue, Zika and chikungunya in Ibagué, a Colombian city and capital of the department of Tolima, with case reports of simultaneous circulation of these three arboviruses. Methods Mosquito collections were carried out monthly between June 2018 and May 2019 in neighborhoods with different levels of socioeconomic status. We used the non-parametric Friedman, Mann–Whitney and Kruskal–Wallis tests to compare mosquito density distributions. We applied logistic regression analyses to identify associations between mosquito density and absence/presence of breeding sites, and the Spearman correlation coefficient to analyze the possible relationship between climatic variables and mosquito density. Results We collected Ae. aegypti in all sampled neighborhoods and found for the first time Ae. albopictus in the city of Ibagué. A greater abundance of mosquitoes was collected in neighborhoods displaying low compared to high socioeconomic status as well as in the intradomicile compared to the peridomestic space. Female mosquitoes predominated over males, and most of the test females had fed on human blood. In total, four Ae. aegypti pools (3%) were positive for dengue virus (serotype 1) and one pool for chikungunya virus (0.8%). Interestingly, infected females were only collected in neighborhoods of low socioeconomic status, and mostly in the intradomicile space. Conclusions We confirmed the co-circulation of dengue (serotype 1) and chikungunya viruses in the Ae. aegypti population in Ibagué. However, Zika virus was not detected in any mosquito sample, 3 years after its introduction into the country. The positivity for dengue and chikungunya viruses, predominance of mosquitoes in the intradomicile space and the high proportion of females fed on humans highlight the high risk for arbovirus transmission in Ibagué, but may also provide an opportunity for establishing effective control strategies. Graphical abstract |
| first_indexed | 2024-12-17T22:37:52Z |
| format | Article |
| id | doaj.art-ca9c1ff8e4ec4105a749830b7979b541 |
| institution | Directory Open Access Journal |
| issn | 1756-3305 |
| language | English |
| last_indexed | 2024-12-17T22:37:52Z |
| publishDate | 2021-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Parasites & Vectors |
| spelling | doaj.art-ca9c1ff8e4ec4105a749830b7979b5412022-12-21T21:30:03ZengBMCParasites & Vectors1756-33052021-09-0114111410.1186/s13071-021-04908-xEntomological characterization of Aedes mosquitoes and arbovirus detection in Ibagué, a Colombian city with co-circulation of Zika, dengue and chikungunya virusesMaría C. Carrasquilla0Mario I. Ortiz1Cielo León2Silvia Rondón3Manisha A. Kulkarni4Benoit Talbot5Beate Sander6Heriberto Vásquez7Juan M. Cordovez8Camila González9RADAM-LAC Research TeamCentro de Investigaciones en Microbiología y Parasitología Tropical (CIMPAT), Universidad de Los AndesCentro de Investigaciones en Microbiología y Parasitología Tropical (CIMPAT), Universidad de Los AndesCentro de Investigaciones en Microbiología y Parasitología Tropical (CIMPAT), Universidad de Los AndesCentro de Investigaciones en Microbiología y Parasitología Tropical (CIMPAT), Universidad de Los AndesSchool of Epidemiology and Public Health, University of OttawaSchool of Epidemiology and Public Health, University of OttawaToronto General Hospital Research Institute, University Health NetworkSecretaría de Salud de IbaguéGrupo de Investigación en Biología Matemática y Computacional (BIOMAC), Universidad de Los AndesCentro de Investigaciones en Microbiología y Parasitología Tropical (CIMPAT), Universidad de Los AndesAbstract Background Dengue, Zika and chikungunya are arboviruses of significant public health importance that are transmitted by Aedes aegypti and Aedes albopictus mosquitoes. In Colombia, where dengue is hyperendemic, and where chikungunya and Zika were introduced in the last decade, more than half of the population lives in areas at risk. The objective of this study was to characterize Aedes spp. vectors and study their natural infection with dengue, Zika and chikungunya in Ibagué, a Colombian city and capital of the department of Tolima, with case reports of simultaneous circulation of these three arboviruses. Methods Mosquito collections were carried out monthly between June 2018 and May 2019 in neighborhoods with different levels of socioeconomic status. We used the non-parametric Friedman, Mann–Whitney and Kruskal–Wallis tests to compare mosquito density distributions. We applied logistic regression analyses to identify associations between mosquito density and absence/presence of breeding sites, and the Spearman correlation coefficient to analyze the possible relationship between climatic variables and mosquito density. Results We collected Ae. aegypti in all sampled neighborhoods and found for the first time Ae. albopictus in the city of Ibagué. A greater abundance of mosquitoes was collected in neighborhoods displaying low compared to high socioeconomic status as well as in the intradomicile compared to the peridomestic space. Female mosquitoes predominated over males, and most of the test females had fed on human blood. In total, four Ae. aegypti pools (3%) were positive for dengue virus (serotype 1) and one pool for chikungunya virus (0.8%). Interestingly, infected females were only collected in neighborhoods of low socioeconomic status, and mostly in the intradomicile space. Conclusions We confirmed the co-circulation of dengue (serotype 1) and chikungunya viruses in the Ae. aegypti population in Ibagué. However, Zika virus was not detected in any mosquito sample, 3 years after its introduction into the country. The positivity for dengue and chikungunya viruses, predominance of mosquitoes in the intradomicile space and the high proportion of females fed on humans highlight the high risk for arbovirus transmission in Ibagué, but may also provide an opportunity for establishing effective control strategies. Graphical abstracthttps://doi.org/10.1186/s13071-021-04908-xDengueZikaChikungunyaAedes aegyptiAedes albopictusColombia |
| spellingShingle | María C. Carrasquilla Mario I. Ortiz Cielo León Silvia Rondón Manisha A. Kulkarni Benoit Talbot Beate Sander Heriberto Vásquez Juan M. Cordovez Camila González RADAM-LAC Research Team Entomological characterization of Aedes mosquitoes and arbovirus detection in Ibagué, a Colombian city with co-circulation of Zika, dengue and chikungunya viruses Parasites & Vectors Dengue Zika Chikungunya Aedes aegypti Aedes albopictus Colombia |
| title | Entomological characterization of Aedes mosquitoes and arbovirus detection in Ibagué, a Colombian city with co-circulation of Zika, dengue and chikungunya viruses |
| title_full | Entomological characterization of Aedes mosquitoes and arbovirus detection in Ibagué, a Colombian city with co-circulation of Zika, dengue and chikungunya viruses |
| title_fullStr | Entomological characterization of Aedes mosquitoes and arbovirus detection in Ibagué, a Colombian city with co-circulation of Zika, dengue and chikungunya viruses |
| title_full_unstemmed | Entomological characterization of Aedes mosquitoes and arbovirus detection in Ibagué, a Colombian city with co-circulation of Zika, dengue and chikungunya viruses |
| title_short | Entomological characterization of Aedes mosquitoes and arbovirus detection in Ibagué, a Colombian city with co-circulation of Zika, dengue and chikungunya viruses |
| title_sort | entomological characterization of aedes mosquitoes and arbovirus detection in ibague a colombian city with co circulation of zika dengue and chikungunya viruses |
| topic | Dengue Zika Chikungunya Aedes aegypti Aedes albopictus Colombia |
| url | https://doi.org/10.1186/s13071-021-04908-x |
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