Polygenic Risk Score and Rare Variant Burden Identified by Targeted Sequencing in a Group of Patients with Pigment Epithelial Detachment in Age-Related Macular Degeneration

Polygenic Risk Score and Rare Variant Burden Identified by Targeted Sequencing in a Group of Patients with Pigment Epithelial Detachment in Age-Related Macular Degeneration

A subset of ophthalmic imaging examination results from 334 patients were subjected to reanalysis to identify a specific group of patients with pigment epithelial detachment (PED) in at least one eye. Overall, we found a subgroup of 47 patients manifesting PED and studied their genotypes in comparis...

Full description

Bibliographic Details
Main Authors: Anna Wąsowska, Adam Sendecki, Anna Boguszewska-Chachulska, Sławomir Teper
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Genes
Subjects:
pigment epithelial detachment
age-related macular degeneration
PED susceptibility
AMD genetics
polygenic model
polygenic risk score
Online Access:https://www.mdpi.com/2073-4425/14/9/1707

Similar Items

Similar Items