Efficacy and MicroRNA-Gut Microbiota Regulatory Mechanisms of Acupuncture for Severe Chronic Constipation: Study Protocol for a Randomized Controlled Trial

Efficacy and MicroRNA-Gut Microbiota Regulatory Mechanisms of Acupuncture for Severe Chronic Constipation: Study Protocol for a Randomized Controlled Trial

BackgroundSevere chronic constipation (SCC) is a common functional gastrointestinal (GI) disorder associated with disruptions in GI motility. Abnormalities between gut microbiota and microRNAs (miRNAs) are implicated in the pathogenesis of GI motility in SCC. Acupuncture has been shown to improve co...

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Bibliographic Details
Main Authors: Junpeng Yao, Xiangyun Yan, Liping Chen, Yanqiu Li, Leixiao Zhang, Min Chen, Ying Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Medicine
Subjects:
severe chronic constipation
acupuncture
gut microbiota
microRNA
protocol
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.906403/full

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