Pathological study of a rare case of lipoblastomatosis with review of literature

<p>Lipoblastomatosis refers to a rare benign tumour of fetal adipose tissue, commonly encountered in early childhood. It presents as a painless, slowly growing mass, usually in superfi cial soft tissues. Microscopy reveals a lobulated architecture with variable admixture of lipoblasts and matu...

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Main Author: N Arathi
Format: Article
Language:English
Published: Association of Clinical Pathologists of Nepal 2013-03-01
Series:Journal of Pathology of Nepal
Subjects:
Online Access:http://www.nepjol.info/index.php/JPN/article/view/7872
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author N Arathi
author_facet N Arathi
author_sort N Arathi
collection DOAJ
description <p>Lipoblastomatosis refers to a rare benign tumour of fetal adipose tissue, commonly encountered in early childhood. It presents as a painless, slowly growing mass, usually in superfi cial soft tissues. Microscopy reveals a lobulated architecture with variable admixture of lipoblasts and mature adipocytes, along with myxoid areas showing spindle shaped cells. The behavior is benign, though recurrences can occur. We present a case of lipoblastomatosis of the right chest wall in a 20 year-old male patient, present since early childhood. The tumour measured 21x13x4 cm; the cut section was grey white to tan. Microscopy revealed mature adipose tissue in most of the areas and an occasional lipoblast. Myxoid areas with spindle cells were seen. Adjacent muscle showed infi ltration by the tumor. This case is presented for its rarity and for having had an opportunity to study the morphology of lipoblastomatosis several years after its onset in early childhood.</p> <p>Journal of Pathology of Nepal (2013) Vol. 3, No.1, Issue 5, 416-418</p> <p>DOI: <a href="http://dx.doi.org/10.3126/jpn.v3i5.7872">http://dx.doi.org/10.3126/jpn.v3i5.7872</a></p>
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spelling doaj.art-caad8d753b7c4ad4b30a5efc4d513d962022-12-21T19:58:08ZengAssociation of Clinical Pathologists of NepalJournal of Pathology of Nepal2091-07972091-09082013-03-013541641810.3126/jpn.v3i5.78726339Pathological study of a rare case of lipoblastomatosis with review of literatureN Arathi0Department of Pathology, SMV Medical College and Research Centre, Madagadipet, Pondicherry,<p>Lipoblastomatosis refers to a rare benign tumour of fetal adipose tissue, commonly encountered in early childhood. It presents as a painless, slowly growing mass, usually in superfi cial soft tissues. Microscopy reveals a lobulated architecture with variable admixture of lipoblasts and mature adipocytes, along with myxoid areas showing spindle shaped cells. The behavior is benign, though recurrences can occur. We present a case of lipoblastomatosis of the right chest wall in a 20 year-old male patient, present since early childhood. The tumour measured 21x13x4 cm; the cut section was grey white to tan. Microscopy revealed mature adipose tissue in most of the areas and an occasional lipoblast. Myxoid areas with spindle cells were seen. Adjacent muscle showed infi ltration by the tumor. This case is presented for its rarity and for having had an opportunity to study the morphology of lipoblastomatosis several years after its onset in early childhood.</p> <p>Journal of Pathology of Nepal (2013) Vol. 3, No.1, Issue 5, 416-418</p> <p>DOI: <a href="http://dx.doi.org/10.3126/jpn.v3i5.7872">http://dx.doi.org/10.3126/jpn.v3i5.7872</a></p>http://www.nepjol.info/index.php/JPN/article/view/7872LipoblastomaLipoblastomatosisMyxoid liposarcomas
spellingShingle N Arathi
Pathological study of a rare case of lipoblastomatosis with review of literature
Journal of Pathology of Nepal
Lipoblastoma
Lipoblastomatosis
Myxoid liposarcomas
title Pathological study of a rare case of lipoblastomatosis with review of literature
title_full Pathological study of a rare case of lipoblastomatosis with review of literature
title_fullStr Pathological study of a rare case of lipoblastomatosis with review of literature
title_full_unstemmed Pathological study of a rare case of lipoblastomatosis with review of literature
title_short Pathological study of a rare case of lipoblastomatosis with review of literature
title_sort pathological study of a rare case of lipoblastomatosis with review of literature
topic Lipoblastoma
Lipoblastomatosis
Myxoid liposarcomas
url http://www.nepjol.info/index.php/JPN/article/view/7872
work_keys_str_mv AT narathi pathologicalstudyofararecaseoflipoblastomatosiswithreviewofliterature