The Association between Non-Alcoholic Fatty Liver Disease and Dynapenia in Men Diagnosed with Type 2 Diabetes Mellitus
<b>Background:</b> Dynapenia and non-alcoholic fatty liver disease (NAFLD) are common, especially in the middle and advanced-age diabetic male population. We aimed to examine the clinical features, NAFLD severity, and parameters associated with the presence of dynapenia in type 2 diabete...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Healthcare |
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| Online Access: | https://www.mdpi.com/2227-9032/11/2/243 |
| _version_ | 1797441924108386304 |
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| author | Atilla Bulur Rıdvan Sivritepe |
| author_facet | Atilla Bulur Rıdvan Sivritepe |
| author_sort | Atilla Bulur |
| collection | DOAJ |
| description | <b>Background:</b> Dynapenia and non-alcoholic fatty liver disease (NAFLD) are common, especially in the middle and advanced-age diabetic male population. We aimed to examine the clinical features, NAFLD severity, and parameters associated with the presence of dynapenia in type 2 diabetes mellitus (T2DM) cases. <b>Material and Methods:</b> One hundred thirty-five male patients diagnosed with T2DM between 45 and 65 years of age were included. Patients were staged by ultrasonography according to NAFLD status. <b>Results:</b> There were significant differences in muscle strength, upper arm circumference, calf circumference, and up-and-go test scores between the mild-moderate-severe and non-NAFLD groups (<i>p</i> < 0.001 for all). The frequency of dynapenia was lower, and arm and calf circumferences were higher in patients without NAFLD. The muscle strength, upper arm circumference, calf circumference, and up-and-go test scores were significantly lower in the dynapenic group compared to the non-dynapenic group (<i>p</i> < 0.005 for all). The prevalence of dynapenia increased along with the increase in NAFLD stages (<i>p</i> < 0.001). <b>Conclusions:</b> We detected a significant association between NAFLD and dynapenia in middle-aged men with T2DM. As muscle strength decreases, the amount of fat in the liver increases, and as the fat in the liver increases, muscle strength decreases. |
| first_indexed | 2024-03-09T12:33:15Z |
| format | Article |
| id | doaj.art-cab0495350fa4f3888f9cabb32c6fd79 |
| institution | Directory Open Access Journal |
| issn | 2227-9032 |
| language | English |
| last_indexed | 2024-03-09T12:33:15Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Healthcare |
| spelling | doaj.art-cab0495350fa4f3888f9cabb32c6fd792023-11-30T22:28:10ZengMDPI AGHealthcare2227-90322023-01-0111224310.3390/healthcare11020243The Association between Non-Alcoholic Fatty Liver Disease and Dynapenia in Men Diagnosed with Type 2 Diabetes MellitusAtilla Bulur0Rıdvan Sivritepe1Gastroenterology and Endoscopy Private Clinic, Aydin 09800, TurkeyDepartment of Internal Medicine, Faculty of Medicine, Istanbul Medipol University, Istanbul 34810, Turkey<b>Background:</b> Dynapenia and non-alcoholic fatty liver disease (NAFLD) are common, especially in the middle and advanced-age diabetic male population. We aimed to examine the clinical features, NAFLD severity, and parameters associated with the presence of dynapenia in type 2 diabetes mellitus (T2DM) cases. <b>Material and Methods:</b> One hundred thirty-five male patients diagnosed with T2DM between 45 and 65 years of age were included. Patients were staged by ultrasonography according to NAFLD status. <b>Results:</b> There were significant differences in muscle strength, upper arm circumference, calf circumference, and up-and-go test scores between the mild-moderate-severe and non-NAFLD groups (<i>p</i> < 0.001 for all). The frequency of dynapenia was lower, and arm and calf circumferences were higher in patients without NAFLD. The muscle strength, upper arm circumference, calf circumference, and up-and-go test scores were significantly lower in the dynapenic group compared to the non-dynapenic group (<i>p</i> < 0.005 for all). The prevalence of dynapenia increased along with the increase in NAFLD stages (<i>p</i> < 0.001). <b>Conclusions:</b> We detected a significant association between NAFLD and dynapenia in middle-aged men with T2DM. As muscle strength decreases, the amount of fat in the liver increases, and as the fat in the liver increases, muscle strength decreases.https://www.mdpi.com/2227-9032/11/2/243type 2 diabetes mellitusnon-alcoholic fatty liver diseasedynapenia |
| spellingShingle | Atilla Bulur Rıdvan Sivritepe The Association between Non-Alcoholic Fatty Liver Disease and Dynapenia in Men Diagnosed with Type 2 Diabetes Mellitus Healthcare type 2 diabetes mellitus non-alcoholic fatty liver disease dynapenia |
| title | The Association between Non-Alcoholic Fatty Liver Disease and Dynapenia in Men Diagnosed with Type 2 Diabetes Mellitus |
| title_full | The Association between Non-Alcoholic Fatty Liver Disease and Dynapenia in Men Diagnosed with Type 2 Diabetes Mellitus |
| title_fullStr | The Association between Non-Alcoholic Fatty Liver Disease and Dynapenia in Men Diagnosed with Type 2 Diabetes Mellitus |
| title_full_unstemmed | The Association between Non-Alcoholic Fatty Liver Disease and Dynapenia in Men Diagnosed with Type 2 Diabetes Mellitus |
| title_short | The Association between Non-Alcoholic Fatty Liver Disease and Dynapenia in Men Diagnosed with Type 2 Diabetes Mellitus |
| title_sort | association between non alcoholic fatty liver disease and dynapenia in men diagnosed with type 2 diabetes mellitus |
| topic | type 2 diabetes mellitus non-alcoholic fatty liver disease dynapenia |
| url | https://www.mdpi.com/2227-9032/11/2/243 |
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