Clinical Applications of Magnetic Resonance-Guided Radiotherapy: A Narrative Review
Magnetic resonance-guided radiotherapy (MRgRT) represents a promising new image guidance technology for radiation treatment delivery combining an onboard MRI scanner with radiation delivery technology. By enabling real-time low-field or high-field MRI acquisition, it facilitates improved soft tissue...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-05-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/15/11/2916 |
| _version_ | 1797597825283915776 |
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| author | Colton Ladbury Arya Amini Amanda Schwer An Liu Terence Williams Percy Lee |
| author_facet | Colton Ladbury Arya Amini Amanda Schwer An Liu Terence Williams Percy Lee |
| author_sort | Colton Ladbury |
| collection | DOAJ |
| description | Magnetic resonance-guided radiotherapy (MRgRT) represents a promising new image guidance technology for radiation treatment delivery combining an onboard MRI scanner with radiation delivery technology. By enabling real-time low-field or high-field MRI acquisition, it facilitates improved soft tissue delineation, adaptive treatment, and motion management. Now that MRgRT has been available for nearly a decade, research has shown the technology can be used to effectively shrink treatment margins to either decrease toxicity (in breast, prostate cancer, and pancreatic cancer) or facilitate dose-escalation and improved oncologic outcomes (in pancreatic and liver cancer), as well as enabling indications that require clear soft tissue delineation and gating (lung and cardiac ablation). In doing so, the use of MRgRT has the potential to significantly improve the outcomes and quality of life of the patients it treats. The present narrative review aims to describe the rationale for MRgRT, the current and forthcoming state of technology, existing studies, and future directions for the advancement of MRgRT, including associated challenges. |
| first_indexed | 2024-03-11T03:10:56Z |
| format | Article |
| id | doaj.art-cab05384efb041abbcb565f4358008dd |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-11T03:10:56Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-cab05384efb041abbcb565f4358008dd2023-11-18T07:38:17ZengMDPI AGCancers2072-66942023-05-011511291610.3390/cancers15112916Clinical Applications of Magnetic Resonance-Guided Radiotherapy: A Narrative ReviewColton Ladbury0Arya Amini1Amanda Schwer2An Liu3Terence Williams4Percy Lee5Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA 91010, USADepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA 91010, USADepartment of Radiation Oncology, City of Hope Orange County Lennar Foundation Cancer Center, Irvine, CA 92618, USADepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA 91010, USADepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA 91010, USADepartment of Radiation Oncology, City of Hope Orange County Lennar Foundation Cancer Center, Irvine, CA 92618, USAMagnetic resonance-guided radiotherapy (MRgRT) represents a promising new image guidance technology for radiation treatment delivery combining an onboard MRI scanner with radiation delivery technology. By enabling real-time low-field or high-field MRI acquisition, it facilitates improved soft tissue delineation, adaptive treatment, and motion management. Now that MRgRT has been available for nearly a decade, research has shown the technology can be used to effectively shrink treatment margins to either decrease toxicity (in breast, prostate cancer, and pancreatic cancer) or facilitate dose-escalation and improved oncologic outcomes (in pancreatic and liver cancer), as well as enabling indications that require clear soft tissue delineation and gating (lung and cardiac ablation). In doing so, the use of MRgRT has the potential to significantly improve the outcomes and quality of life of the patients it treats. The present narrative review aims to describe the rationale for MRgRT, the current and forthcoming state of technology, existing studies, and future directions for the advancement of MRgRT, including associated challenges.https://www.mdpi.com/2072-6694/15/11/2916magnetic resonance-guided radiotherapy (MRgRT)image-guided radiation therapy (IGRT)magnetic resonance imaging (MRI) |
| spellingShingle | Colton Ladbury Arya Amini Amanda Schwer An Liu Terence Williams Percy Lee Clinical Applications of Magnetic Resonance-Guided Radiotherapy: A Narrative Review Cancers magnetic resonance-guided radiotherapy (MRgRT) image-guided radiation therapy (IGRT) magnetic resonance imaging (MRI) |
| title | Clinical Applications of Magnetic Resonance-Guided Radiotherapy: A Narrative Review |
| title_full | Clinical Applications of Magnetic Resonance-Guided Radiotherapy: A Narrative Review |
| title_fullStr | Clinical Applications of Magnetic Resonance-Guided Radiotherapy: A Narrative Review |
| title_full_unstemmed | Clinical Applications of Magnetic Resonance-Guided Radiotherapy: A Narrative Review |
| title_short | Clinical Applications of Magnetic Resonance-Guided Radiotherapy: A Narrative Review |
| title_sort | clinical applications of magnetic resonance guided radiotherapy a narrative review |
| topic | magnetic resonance-guided radiotherapy (MRgRT) image-guided radiation therapy (IGRT) magnetic resonance imaging (MRI) |
| url | https://www.mdpi.com/2072-6694/15/11/2916 |
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