Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells

Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells

Neural progenitor cells (NPCs) from human induced pluripotent stem cells (hiPSCs) are frequently induced using 3D culture methodologies however, it is unknown whether spheroid-based (3D) neural induction is actually superior to monolayer (2D) neural induction. Our aim was to compare the efficiency o...

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Bibliographic Details
Main Authors: Abinaya Chandrasekaran, Hasan X. Avci, Anna Ochalek, Lone N. Rösingh, Kinga Molnár, Lajos László, Tamás Bellák, Annamária Téglási, Krisztina Pesti, Arpad Mike, Phetcharat Phanthong, Orsolya Bíró, Vanessa Hall, Narisorn Kitiyanant, Karl-Heinz Krause, Julianna Kobolák, András Dinnyés
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Stem Cell Research
Subjects:
Neural induction
Neural progenitor cells
hiPSC
Electron microscopy
Patch clamp
2D-3D neural induction
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506117302131

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