Effect of Lattice Structure and Composite Precursor on Mechanical Properties of 3D-Printed Bone Scaffolds
This article presents an investigation on designing and fabricating scaffolds with different structures, desired porosity, composition, and surface area to volume ratio (SA:V) for orthopedic applications by using the computer-aided design (CAD) and the stereolithography (SLA) 3D printing technique....
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
al-Farabi Kazakh National University
2021-12-01
|
| Series: | Eurasian Chemico-Technological Journal |
| Subjects: | |
| Online Access: | https://ect-journal.kz/index.php/ectj/article/view/1129 |
| _version_ | 1811335521292517376 |
|---|---|
| author | M. Shams Z. Mansurov C. Daulbayev B. Bakbolat |
| author_facet | M. Shams Z. Mansurov C. Daulbayev B. Bakbolat |
| author_sort | M. Shams |
| collection | DOAJ |
| description |
This article presents an investigation on designing and fabricating scaffolds with different structures, desired porosity, composition, and surface area to volume ratio (SA:V) for orthopedic applications by using the computer-aided design (CAD) and the stereolithography (SLA) 3D printing technique. Different triply periodic minimal surfaces (TPMS) and functionally graded lattice structures (FGLS) were designed based on various cell geometries. Finite element analysis (FEA), tensile and compression tests were carried out, and the results are presented. Two different resin compositions were used to print the models and compare the effect of resin precursors on the mechanical properties of scaffolds. The first was a biodegradable resin made from soybean oil commercially available on the market (made by Anycubic Co.). The second was a mixture of biodegradable UV-cured resin with 5% W/W of hydroxyapatite (HA) and 5% W/W calcium pyrophosphate (CPP). Bio-Hydroxyapatite and Bio-Calcium Pyrophosphate were obtained from eggshells waste and characterized using XRD and FESEM. The obtained data show that adding resin precursors (HA/CPP) slightly decreases the mechanical strength of printed scaffolds; however, considering their extraordinary effect on bone regeneration, this small effect can be ignored, and HA/CPP can be used as an ideal agent in bioscaffolds.
|
| first_indexed | 2024-04-13T17:25:18Z |
| format | Article |
| id | doaj.art-cab7afbb2b214e15b4d03efce03a0a0e |
| institution | Directory Open Access Journal |
| issn | 1562-3920 2522-4867 |
| language | English |
| last_indexed | 2024-04-13T17:25:18Z |
| publishDate | 2021-12-01 |
| publisher | al-Farabi Kazakh National University |
| record_format | Article |
| series | Eurasian Chemico-Technological Journal |
| spelling | doaj.art-cab7afbb2b214e15b4d03efce03a0a0e2022-12-22T02:37:49Zengal-Farabi Kazakh National UniversityEurasian Chemico-Technological Journal1562-39202522-48672021-12-0123410.18321/ectj1129Effect of Lattice Structure and Composite Precursor on Mechanical Properties of 3D-Printed Bone ScaffoldsM. Shams0Z. Mansurov1C. Daulbayev2B. Bakbolat3al-Farabi Kazakh National University, 71 Al-Farabi ave., Almaty, Kazakhstan; Institute of Combustion Problems, 172 Bogenbay batyr str., Almaty, Kazakhstanal-Farabi Kazakh National University, 71 Al-Farabi ave., Almaty, Kazakhstan; Institute of Combustion Problems, 172 Bogenbay batyr str., Almaty, Kazakhstanal-Farabi Kazakh National University, 71 Al-Farabi ave., Almaty, Kazakhstan; Institute of Combustion Problems, 172 Bogenbay batyr str., Almaty, Kazakhstanal-Farabi Kazakh National University, 71 Al-Farabi ave., Almaty, Kazakhstan; Institute of Combustion Problems, 172 Bogenbay batyr str., Almaty, Kazakhstan This article presents an investigation on designing and fabricating scaffolds with different structures, desired porosity, composition, and surface area to volume ratio (SA:V) for orthopedic applications by using the computer-aided design (CAD) and the stereolithography (SLA) 3D printing technique. Different triply periodic minimal surfaces (TPMS) and functionally graded lattice structures (FGLS) were designed based on various cell geometries. Finite element analysis (FEA), tensile and compression tests were carried out, and the results are presented. Two different resin compositions were used to print the models and compare the effect of resin precursors on the mechanical properties of scaffolds. The first was a biodegradable resin made from soybean oil commercially available on the market (made by Anycubic Co.). The second was a mixture of biodegradable UV-cured resin with 5% W/W of hydroxyapatite (HA) and 5% W/W calcium pyrophosphate (CPP). Bio-Hydroxyapatite and Bio-Calcium Pyrophosphate were obtained from eggshells waste and characterized using XRD and FESEM. The obtained data show that adding resin precursors (HA/CPP) slightly decreases the mechanical strength of printed scaffolds; however, considering their extraordinary effect on bone regeneration, this small effect can be ignored, and HA/CPP can be used as an ideal agent in bioscaffolds. https://ect-journal.kz/index.php/ectj/article/view/1129bone scaffolds3D printinghydroxyapatitestereolithographycalcium pyrophosphatebioscaffold |
| spellingShingle | M. Shams Z. Mansurov C. Daulbayev B. Bakbolat Effect of Lattice Structure and Composite Precursor on Mechanical Properties of 3D-Printed Bone Scaffolds Eurasian Chemico-Technological Journal bone scaffolds 3D printing hydroxyapatite stereolithography calcium pyrophosphate bioscaffold |
| title | Effect of Lattice Structure and Composite Precursor on Mechanical Properties of 3D-Printed Bone Scaffolds |
| title_full | Effect of Lattice Structure and Composite Precursor on Mechanical Properties of 3D-Printed Bone Scaffolds |
| title_fullStr | Effect of Lattice Structure and Composite Precursor on Mechanical Properties of 3D-Printed Bone Scaffolds |
| title_full_unstemmed | Effect of Lattice Structure and Composite Precursor on Mechanical Properties of 3D-Printed Bone Scaffolds |
| title_short | Effect of Lattice Structure and Composite Precursor on Mechanical Properties of 3D-Printed Bone Scaffolds |
| title_sort | effect of lattice structure and composite precursor on mechanical properties of 3d printed bone scaffolds |
| topic | bone scaffolds 3D printing hydroxyapatite stereolithography calcium pyrophosphate bioscaffold |
| url | https://ect-journal.kz/index.php/ectj/article/view/1129 |
| work_keys_str_mv | AT mshams effectoflatticestructureandcompositeprecursoronmechanicalpropertiesof3dprintedbonescaffolds AT zmansurov effectoflatticestructureandcompositeprecursoronmechanicalpropertiesof3dprintedbonescaffolds AT cdaulbayev effectoflatticestructureandcompositeprecursoronmechanicalpropertiesof3dprintedbonescaffolds AT bbakbolat effectoflatticestructureandcompositeprecursoronmechanicalpropertiesof3dprintedbonescaffolds |