High flow nasal therapy during early pulmonary rehabilitation in patients with acute severe exacerbation of COPD: beneficial or illusory?
Abstract In study “Effect of high-flow nasal therapy during early pulmonary rehabilitation in patients with severe AECOPD: a randomized controlled study” by Tung et al., authors concluded HFNT utilization led to enhanced exercise tolerance and a reduction of systemic inflammation. Nevertheless, some...
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| Format: | Article |
| Language: | English |
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BMC
2020-06-01
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| Series: | Respiratory Research |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12931-020-01415-y |
| _version_ | 1811286028444499968 |
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| author | Guillaume Prieur Yann Combret Clement Medrinal |
| author_facet | Guillaume Prieur Yann Combret Clement Medrinal |
| author_sort | Guillaume Prieur |
| collection | DOAJ |
| description | Abstract In study “Effect of high-flow nasal therapy during early pulmonary rehabilitation in patients with severe AECOPD: a randomized controlled study” by Tung et al., authors concluded HFNT utilization led to enhanced exercise tolerance and a reduction of systemic inflammation. Nevertheless, some points requires additional discussion, the conclusion of the trial seems overstated. The baseline differences between groups induces substantial modifications in the conclusions of this trial. HFNT does not seem to add any benefit on exercise tolerance or systemic inflammation, nor on pulmonary function. The only difference that remained significant in homogenous statistical significance is dyspnea on the mMRC scale but clinical significance is highly questionable. |
| first_indexed | 2024-04-13T02:53:30Z |
| format | Article |
| id | doaj.art-cabf3f15b5944ac2b0acd94909ba9f63 |
| institution | Directory Open Access Journal |
| issn | 1465-993X |
| language | English |
| last_indexed | 2024-04-13T02:53:30Z |
| publishDate | 2020-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Respiratory Research |
| spelling | doaj.art-cabf3f15b5944ac2b0acd94909ba9f632022-12-22T03:05:46ZengBMCRespiratory Research1465-993X2020-06-012111210.1186/s12931-020-01415-yHigh flow nasal therapy during early pulmonary rehabilitation in patients with acute severe exacerbation of COPD: beneficial or illusory?Guillaume Prieur0Yann Combret1Clement Medrinal2Institut de Recherche Expérimentale et Clinique (IREC), Pôle de Pneumologie, ORL & Dermatologie, Groupe de Recherche en Kinésithérapie Respiratoire, Université Catholique de LouvainInstitut de Recherche Expérimentale et Clinique (IREC), Pôle de Pneumologie, ORL & Dermatologie, Groupe de Recherche en Kinésithérapie Respiratoire, Université Catholique de LouvainInstitute for Research and Innovation in Biomedicine (IRIB), Normandie Univ, UNIROUEN, EA3830-GRHVAbstract In study “Effect of high-flow nasal therapy during early pulmonary rehabilitation in patients with severe AECOPD: a randomized controlled study” by Tung et al., authors concluded HFNT utilization led to enhanced exercise tolerance and a reduction of systemic inflammation. Nevertheless, some points requires additional discussion, the conclusion of the trial seems overstated. The baseline differences between groups induces substantial modifications in the conclusions of this trial. HFNT does not seem to add any benefit on exercise tolerance or systemic inflammation, nor on pulmonary function. The only difference that remained significant in homogenous statistical significance is dyspnea on the mMRC scale but clinical significance is highly questionable.http://link.springer.com/article/10.1186/s12931-020-01415-yCOPDExacerbationHigh flow nasalPulmonary rehabilitation |
| spellingShingle | Guillaume Prieur Yann Combret Clement Medrinal High flow nasal therapy during early pulmonary rehabilitation in patients with acute severe exacerbation of COPD: beneficial or illusory? Respiratory Research COPD Exacerbation High flow nasal Pulmonary rehabilitation |
| title | High flow nasal therapy during early pulmonary rehabilitation in patients with acute severe exacerbation of COPD: beneficial or illusory? |
| title_full | High flow nasal therapy during early pulmonary rehabilitation in patients with acute severe exacerbation of COPD: beneficial or illusory? |
| title_fullStr | High flow nasal therapy during early pulmonary rehabilitation in patients with acute severe exacerbation of COPD: beneficial or illusory? |
| title_full_unstemmed | High flow nasal therapy during early pulmonary rehabilitation in patients with acute severe exacerbation of COPD: beneficial or illusory? |
| title_short | High flow nasal therapy during early pulmonary rehabilitation in patients with acute severe exacerbation of COPD: beneficial or illusory? |
| title_sort | high flow nasal therapy during early pulmonary rehabilitation in patients with acute severe exacerbation of copd beneficial or illusory |
| topic | COPD Exacerbation High flow nasal Pulmonary rehabilitation |
| url | http://link.springer.com/article/10.1186/s12931-020-01415-y |
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