Lack of XBP-1 impedes murine cytomegalovirus gene expression.

Lack of XBP-1 impedes murine cytomegalovirus gene expression.

The unfolded protein response (UPR) is an endoplasmic reticulum (ER)-to-nucleus signaling cascade induced in response to ER stress. The UPR aims at restoring homeostasis, but can also induce apoptosis if stress persists. Infection by human and murine cytomegaloviruses (CMVs) provokes ER stress and i...

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Bibliographic Details
Main Authors: Adi Drori, Martin Messerle, Wolfram Brune, Boaz Tirosh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4205010?pdf=render

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