Practical and Sustainable Synthesis of Optically Pure Levocabastine, a H1 Receptor Antagonist

Practical and Sustainable Synthesis of Optically Pure Levocabastine, a H1 Receptor Antagonist

A practical and sustainable method for the synthesis of levocabastine hydrochloride (1), a H1 receptor antagonist for the treatment of allergic conjunctivitis, that can be applied to the industrial production of the compound has been developed. Substantial improvements over the previously reported p...

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Bibliographic Details
Main Authors: Sung Kwon Kang, Dong Hyuk Nam, Jaeseung Ahn, Jaemin Lee, Jaehoon Sim, Jeeyeon Lee, Young-Ger Suh
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Molecules
Subjects:
levocabastine
anti-histamine
H1 receptor antagonist
Online Access:https://www.mdpi.com/1420-3049/22/11/1971

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