CIP4 targeted to recruit GTP-Cdc42 involving in invadopodia formation via NF-κB signaling pathway promotes invasion and metastasis of CRC

CIP4 targeted to recruit GTP-Cdc42 involving in invadopodia formation via NF-κB signaling pathway promotes invasion and metastasis of CRC

Cdc42-interacting protein 4 (CIP4), a member of the F-BAR family, which plays an important role in regulating cell membrane and actin, has been reported to interact with Cdc42 and be closely associated with tumor invadopodia formation. In this study, we found that CIP4 expression was significantly h...

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Bibliographic Details
Main Authors: Zhiyan Hu, Jiaxian Zhu, Yidan Ma, Ting Long, Lingfang Gao, Yan Zhong, Xiaoyan Wang, Zuguo Li
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Molecular Therapy: Oncolytics
Subjects:
CIP4
Cdc42
NF-κB
invadopodia
colorectal cancer
invasion
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770522000407

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