Comparative effectiveness of myocardial cytoprotectors in chronic heart failure treatment

The study is focused on comparative effectiveness of myocardial cytoprotectors in chronic heart failure (CHF) treatment. In total, 120 patients with Functional Class (FC) II-III CHF were divided into two groups. For 60 days, Group I received mildronate, 1.0 g/d, Group II - preductal MV (trimetazidin...

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Main Authors: G. G. Semenkova, L. V. Kokoreva
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2007-04-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/2082
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author G. G. Semenkova
L. V. Kokoreva
author_facet G. G. Semenkova
L. V. Kokoreva
author_sort G. G. Semenkova
collection DOAJ
description The study is focused on comparative effectiveness of myocardial cytoprotectors in chronic heart failure (CHF) treatment. In total, 120 patients with Functional Class (FC) II-III CHF were divided into two groups. For 60 days, Group I received mildronate, 1.0 g/d, Group II - preductal MV (trimetazidine), 60 mg/d, in addition to standard treatment. Control group received standard treatment only (n=20). Clinical examination was performed at Days 1, 14, and 60. Therapy effectiveness was assessed by subjective, objective, laboratory and instrumental data dynamics. In mildronate group, the parameters assessed had improved significantly, comparing to control and preductal MV groups.
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spelling doaj.art-cac5a769549c4e9389c4c56647d485942023-03-29T21:23:14Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202007-04-010277821836Comparative effectiveness of myocardial cytoprotectors in chronic heart failure treatmentG. G. Semenkova0L. V. Kokoreva1Воронежская государственная медицинская академия им. Н.Н. БурденкоВоронежская государственная медицинская академия им. Н.Н. БурденкоThe study is focused on comparative effectiveness of myocardial cytoprotectors in chronic heart failure (CHF) treatment. In total, 120 patients with Functional Class (FC) II-III CHF were divided into two groups. For 60 days, Group I received mildronate, 1.0 g/d, Group II - preductal MV (trimetazidine), 60 mg/d, in addition to standard treatment. Control group received standard treatment only (n=20). Clinical examination was performed at Days 1, 14, and 60. Therapy effectiveness was assessed by subjective, objective, laboratory and instrumental data dynamics. In mildronate group, the parameters assessed had improved significantly, comparing to control and preductal MV groups.https://russjcardiol.elpub.ru/jour/article/view/2082chronic heart failuremyocardial cytoprotectorstherapy effectiveness
spellingShingle G. G. Semenkova
L. V. Kokoreva
Comparative effectiveness of myocardial cytoprotectors in chronic heart failure treatment
Российский кардиологический журнал
chronic heart failure
myocardial cytoprotectors
therapy effectiveness
title Comparative effectiveness of myocardial cytoprotectors in chronic heart failure treatment
title_full Comparative effectiveness of myocardial cytoprotectors in chronic heart failure treatment
title_fullStr Comparative effectiveness of myocardial cytoprotectors in chronic heart failure treatment
title_full_unstemmed Comparative effectiveness of myocardial cytoprotectors in chronic heart failure treatment
title_short Comparative effectiveness of myocardial cytoprotectors in chronic heart failure treatment
title_sort comparative effectiveness of myocardial cytoprotectors in chronic heart failure treatment
topic chronic heart failure
myocardial cytoprotectors
therapy effectiveness
url https://russjcardiol.elpub.ru/jour/article/view/2082
work_keys_str_mv AT ggsemenkova comparativeeffectivenessofmyocardialcytoprotectorsinchronicheartfailuretreatment
AT lvkokoreva comparativeeffectivenessofmyocardialcytoprotectorsinchronicheartfailuretreatment