Guillain-Barre like syndrome associated with risperidone use: A case report (eng)

Guillain-Barre Syndrome is an autoimmune response that usually occurs due to infectious or idiopathic causes. Rare case reports have also been shown to be caused by the intake of many substances and drugs. GBS cases results in 10% mortality and 25% respiratory failure. This case report describes the...

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Main Author: Güneş Devrim Kıcalı
Format: Article
Language:English
Published: ANP Publishing 2022-12-01
Series:Klinik Psikiyatri Dergisi
Subjects:
Online Access:https://jag.journalagent.com/z4/download_fulltext.asp?pdir=kpd&un=KPD-70846
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author Güneş Devrim Kıcalı
author_facet Güneş Devrim Kıcalı
author_sort Güneş Devrim Kıcalı
collection DOAJ
description Guillain-Barre Syndrome is an autoimmune response that usually occurs due to infectious or idiopathic causes. Rare case reports have also been shown to be caused by the intake of many substances and drugs. GBS cases results in 10% mortality and 25% respiratory failure. This case report describes the occurrence and termination of GBS-like syndrome following first time risperidone intake at a patient in the psychiatric ward. A 42-years old female patient without any prior psychiatric history admitted to psychiatric ward with paranoid and persecutory delusions, disorganized speech and behaviors related to systematic delusions aiming infidelity of her spouse. Risperidone 4 mg day prescribed for treatment for first time. In seventh day, neuromuscular symptoms started as dizziness, ataxia, muscle weakness and ascending paralysis. Neurological examination and consultation, imaging and lumbar puncture was performed, resulting GBS diagnosis. With the immediate transfer to intense care unit, Risperidone treatment stopped and hIG treatment administered. Patient Recovered without any physical impairment. Current case presents a GBS like syndrome associated with Risperidone treatment. There are several Atypical antipsychotic drug treatment related GBS like case reports but this is the first to be associated with Risperidone in adults. Infection related etiology was excluded by patient history but no specific antibody test or immunological survey was performed for GBS.
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spelling doaj.art-cac5fba3a1a747cdb0adb4a1a4b0c2bb2023-02-15T16:18:32ZengANP PublishingKlinik Psikiyatri Dergisi1302-00992022-12-0125442642910.5505/kpd.2022.70846KPD-70846Guillain-Barre like syndrome associated with risperidone use: A case report (eng)Güneş Devrim Kıcalı0Mugla Training and Research Hospital, Department of PsychiatryGuillain-Barre Syndrome is an autoimmune response that usually occurs due to infectious or idiopathic causes. Rare case reports have also been shown to be caused by the intake of many substances and drugs. GBS cases results in 10% mortality and 25% respiratory failure. This case report describes the occurrence and termination of GBS-like syndrome following first time risperidone intake at a patient in the psychiatric ward. A 42-years old female patient without any prior psychiatric history admitted to psychiatric ward with paranoid and persecutory delusions, disorganized speech and behaviors related to systematic delusions aiming infidelity of her spouse. Risperidone 4 mg day prescribed for treatment for first time. In seventh day, neuromuscular symptoms started as dizziness, ataxia, muscle weakness and ascending paralysis. Neurological examination and consultation, imaging and lumbar puncture was performed, resulting GBS diagnosis. With the immediate transfer to intense care unit, Risperidone treatment stopped and hIG treatment administered. Patient Recovered without any physical impairment. Current case presents a GBS like syndrome associated with Risperidone treatment. There are several Atypical antipsychotic drug treatment related GBS like case reports but this is the first to be associated with Risperidone in adults. Infection related etiology was excluded by patient history but no specific antibody test or immunological survey was performed for GBS.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=kpd&un=KPD-70846antipsychoticsrisperidoneguillain-barre syndromeneuropsychiatry
spellingShingle Güneş Devrim Kıcalı
Guillain-Barre like syndrome associated with risperidone use: A case report (eng)
Klinik Psikiyatri Dergisi
antipsychotics
risperidone
guillain-barre syndrome
neuropsychiatry
title Guillain-Barre like syndrome associated with risperidone use: A case report (eng)
title_full Guillain-Barre like syndrome associated with risperidone use: A case report (eng)
title_fullStr Guillain-Barre like syndrome associated with risperidone use: A case report (eng)
title_full_unstemmed Guillain-Barre like syndrome associated with risperidone use: A case report (eng)
title_short Guillain-Barre like syndrome associated with risperidone use: A case report (eng)
title_sort guillain barre like syndrome associated with risperidone use a case report eng
topic antipsychotics
risperidone
guillain-barre syndrome
neuropsychiatry
url https://jag.journalagent.com/z4/download_fulltext.asp?pdir=kpd&un=KPD-70846
work_keys_str_mv AT gunesdevrimkıcalı guillainbarrelikesyndromeassociatedwithrisperidoneuseacasereporteng