A Silent Threat of Emerging Resistance Based on Antifungal Susceptibility Pattern of Filamentous Fungi by Microdilution, E Test and, Disc Diffusion Method: A Critical Constructive Analysis
For more than two decades, antifungal susceptibility testing and interpretation haunted the medical professionals in diagnostics and management. This article mainly focuses on the three most widely used methods: broth microdilution, E test, and disc diffusion. It also focuses on the fact that clinic...
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Format: | Article |
Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2022-07-01
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Series: | Annals of the National Academy of Medical Sciences (India) |
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Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1750417 |
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author | Uneza Husain Ketan Priyadarshi |
author_facet | Uneza Husain Ketan Priyadarshi |
author_sort | Uneza Husain |
collection | DOAJ |
description | For more than two decades, antifungal susceptibility testing and interpretation haunted the medical professionals in diagnostics and management. This article mainly focuses on the three most widely used methods: broth microdilution, E test, and disc diffusion. It also focuses on the fact that clinicians should switch from empirical treatment to susceptible drugs as early as possible to combat antifungal resistance and newer mutations that horrify us every single day with poor patient outcomes. Many factors need to be taken into account during the interpretation of results but the positive side of the story is that they have been well documented in the literature. Though many methods have come up in testing antifungal susceptibility, still there is a scope for a rapid yet accurate testing modality to flourish and take the lead. |
first_indexed | 2024-04-12T02:11:45Z |
format | Article |
id | doaj.art-cacb4d19006a4152ae7333fa29ea2d7e |
institution | Directory Open Access Journal |
issn | 0379-038X 2454-5635 |
language | English |
last_indexed | 2024-04-12T02:11:45Z |
publishDate | 2022-07-01 |
publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
record_format | Article |
series | Annals of the National Academy of Medical Sciences (India) |
spelling | doaj.art-cacb4d19006a4152ae7333fa29ea2d7e2022-12-22T03:52:23ZengThieme Medical and Scientific Publishers Pvt. Ltd.Annals of the National Academy of Medical Sciences (India)0379-038X2454-56352022-07-01580312512710.1055/s-0042-1750417A Silent Threat of Emerging Resistance Based on Antifungal Susceptibility Pattern of Filamentous Fungi by Microdilution, E Test and, Disc Diffusion Method: A Critical Constructive AnalysisUneza Husain0Ketan Priyadarshi1Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, IndiaDepartment of Microbiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, IndiaFor more than two decades, antifungal susceptibility testing and interpretation haunted the medical professionals in diagnostics and management. This article mainly focuses on the three most widely used methods: broth microdilution, E test, and disc diffusion. It also focuses on the fact that clinicians should switch from empirical treatment to susceptible drugs as early as possible to combat antifungal resistance and newer mutations that horrify us every single day with poor patient outcomes. Many factors need to be taken into account during the interpretation of results but the positive side of the story is that they have been well documented in the literature. Though many methods have come up in testing antifungal susceptibility, still there is a scope for a rapid yet accurate testing modality to flourish and take the lead.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1750417filamentous fungibroth microdilutionbmddisc diffusione test |
spellingShingle | Uneza Husain Ketan Priyadarshi A Silent Threat of Emerging Resistance Based on Antifungal Susceptibility Pattern of Filamentous Fungi by Microdilution, E Test and, Disc Diffusion Method: A Critical Constructive Analysis Annals of the National Academy of Medical Sciences (India) filamentous fungi broth microdilution bmd disc diffusion e test |
title | A Silent Threat of Emerging Resistance Based on Antifungal Susceptibility Pattern of Filamentous Fungi by Microdilution, E Test and, Disc Diffusion Method: A Critical Constructive Analysis |
title_full | A Silent Threat of Emerging Resistance Based on Antifungal Susceptibility Pattern of Filamentous Fungi by Microdilution, E Test and, Disc Diffusion Method: A Critical Constructive Analysis |
title_fullStr | A Silent Threat of Emerging Resistance Based on Antifungal Susceptibility Pattern of Filamentous Fungi by Microdilution, E Test and, Disc Diffusion Method: A Critical Constructive Analysis |
title_full_unstemmed | A Silent Threat of Emerging Resistance Based on Antifungal Susceptibility Pattern of Filamentous Fungi by Microdilution, E Test and, Disc Diffusion Method: A Critical Constructive Analysis |
title_short | A Silent Threat of Emerging Resistance Based on Antifungal Susceptibility Pattern of Filamentous Fungi by Microdilution, E Test and, Disc Diffusion Method: A Critical Constructive Analysis |
title_sort | silent threat of emerging resistance based on antifungal susceptibility pattern of filamentous fungi by microdilution e test and disc diffusion method a critical constructive analysis |
topic | filamentous fungi broth microdilution bmd disc diffusion e test |
url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1750417 |
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