Early OA Stage Like Response Occurs after Dynamic Stretching of Human Synovial Fibroblasts

Early OA Stage Like Response Occurs after Dynamic Stretching of Human Synovial Fibroblasts

As events triggering early osteoarthritis onset can be related to mechanical stress and proinflammatory signaling, we investigated the effect of different mechanical strain protocols on the expression of proinflammatory genes, as well as extracellular matrix remodelling in human synovial fibroblasts...

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Bibliographic Details
Main Authors: Ute Nazet, Susanne Grässel, Jonathan Jantsch, Peter Proff, Agnes Schröder, Christian Kirschneck
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
osteoarthritis
synovial fibroblasts
mechanical strain
inflammation
Online Access:https://www.mdpi.com/1422-0067/21/11/3874

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