Temperature modulates PVN pre-sympathetic neurones via transient receptor potential ion channels

Temperature modulates PVN pre-sympathetic neurones via transient receptor potential ion channels

The paraventricular nucleus (PVN) of the hypothalamus plays a vital role in maintaining homeostasis and modulates cardiovascular function via autonomic pre-sympathetic neurones. We have previously shown that coupling between transient receptor potential cation channel subfamily V Member 4 (Trpv4) an...

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Bibliographic Details
Main Authors: Fiona O’Brien, Claire H. Feetham, Caroline A. Staunton, Kathryn Hext, Richard Barrett-Jolley
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Pharmacology
Subjects:
PVN
PVH
thermoregulation
ion channel
TRPV4
computational model
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1256924/full

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