Coumarins from <i>Seseli devenyense</i> Simonk.: Isolation by Liquid–Liquid Chromatography and Potential Anxiolytic Activity Using an In Vivo Zebrafish Larvae Model

Coumarins from <i>Seseli devenyense</i> Simonk.: Isolation by Liquid–Liquid Chromatography and Potential Anxiolytic Activity Using an In Vivo Zebrafish Larvae Model

Different types of anxiety disorders have become the number one mental health issue in developed countries. The search for new, safer and effective drug-like molecules among naturally derived substances faces two difficulties: an efficient method of isolation compounds with a high-purity and high-th...

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Bibliographic Details
Main Authors: Jarosław Widelski, Simon Vlad Luca, Adrianna Skiba, Monika Maciąg, Barbara Budzyńska, Laurence Marcourt, Jean-Luc Wolfender, Krystyna Skalicka-Woźniak
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Seseli devenyense</i>
Apiaceae
countercurrent chromatography
central nervous system
anxiety
<i>Danio rerio</i>
Online Access:https://www.mdpi.com/1422-0067/22/4/1829

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