Backward bifurcation on HIV/AIDS SEI1I2TAR model with multiple interactions between sub-populations

AbstractThe HIV/AIDS model was dynamically analyzed in this study. The model has seven compartments: the uneducated, the educated, the HIV-positive who take antiretroviral therapy (ART), the HIV-positive who do not take ART, people receiving ART treatment, people with AIDS who do not receive any tre...

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Bibliographic Details
Main Authors: Ummu Habibah, Trisilowati, Tiara Rizki Tania, Labib Umam Al-Faruq
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Arab Journal of Basic and Applied Sciences
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/25765299.2023.2286713
Description
Summary:AbstractThe HIV/AIDS model was dynamically analyzed in this study. The model has seven compartments: the uneducated, the educated, the HIV-positive who take antiretroviral therapy (ART), the HIV-positive who do not take ART, people receiving ART treatment, people with AIDS who do not receive any treatment (full-blown AIDS), and the recovered. This model takes into account the analysis of the multiple interactions between the uneducated and the educated subpopulations, the HIV-positive who take and who do not take ART. The free-disease and endemic equilibrium points, as well as the basic reproduction number [Formula: see text] as a limit condition for infection-free and endemic occurrence, were produced by a mathematical analysis. The center-manifold hypothesis was used to prove that a backward bifurcation exists. The free-disease and endemic equilibrium points coexist when [Formula: see text] This means that HIV/AIDS is still spreading. A basic reproduction number below one is insufficient to constitute a free-disease condition. In order to determine essential parameters that significantly contribute to HIV/AIDS transmission, we computed sensitivity index values using a sensitivity analysis. The HIV/AIDS model and bifurcation parameter both identified the rate of HIV transmission from uneducated individuals to HIV-positive individuals who do not receive ART as the most crucial parameter. A numerical simulation supports the dynamical analysis.
ISSN:2576-5299