The Art of Capturing Pluripotency: Creating the Right Culture

The Art of Capturing Pluripotency: Creating the Right Culture

Embryonic stem cells (ESCs) are a unique tool for genetic perturbation of mammalian cellular and organismal processes additionally in humans offer unprecedented opportunities for disease modeling and cell therapy. Furthermore, ESCs are a powerful system for exploring the fundamental biology of pluri...

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Bibliographic Details
Main Authors: Qi-Long Ying, Austin Smith
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Stem Cell Reports
Subjects:
embryonic stem cell
epiblast stem cell
naive pluripotency
primed pluripotency
stem cell self-renewal
stem cell differentiation
LIF/Stat3
Wnt/β-catenin
MEK
ERK
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117302278

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http://www.sciencedirect.com/science/article/pii/S2213671117302278

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