Progressive macrophage accumulation in lysosomal acid lipase deficiency

Progressive macrophage accumulation in lysosomal acid lipase deficiency

Lysosomal acid lipase (LAL) deficiency (LAL-D) is a lysosomal lipid storage disorder in which the accumulation of cholesteryl esters and triglycerides predominantly in hepatocytes and cells of the macrophage-monocyte system is observed. The disturbance in the synthesis and trafficking of cholesterol...

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Bibliographic Details
Main Authors:	Patryk Lipiński, Joanna Cielecka-Kuszyk, Anna Bożkiewicz-Kasperczyk, Barbara Perkowska, Elżbieta Jurkiewicz, Anna Tylki-Szymańska
Format:	Article
Language:	English
Published:	Elsevier 2020-06-01
Series:	Molecular Genetics and Metabolism Reports
Subjects:	Lysosomal acid lipase Lysosomal acid lipase deficiency Macrophage Lymphadenitis CD68
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214426920300409

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