The Hyperphagia Questionnaire: Insights From a Multicentric Validation Study in Individuals With Prader Willi Syndrome
Background/ObjectivesThe present study aimed to validate the Italian version of the Hyperphagia Questionnaire (HQ), a 11-items questionnaire developed to assess hyperphagia in individuals with Prader-Willi syndrome (PWS). This is a complex neurodevelopmental disorder characterized by endocrine dysfu...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-02-01
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| Series: | Frontiers in Pediatrics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2022.829486/full |
| _version_ | 1824045564814163968 |
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| author | Maria Rosaria Licenziati Dario Bacchini Antonino Crinò Graziano Grugni Danilo Fintini Sara Osimani Letizia Ragusa Michele Sacco Lorenzo Iughetti Luisa De Sanctis Adriana Franzese Malgorzata Gabriela Wasniewska Maria Felicia Faienza Maurizio Delvecchio Concetta Esposito Giuliana Valerio |
| author_facet | Maria Rosaria Licenziati Dario Bacchini Antonino Crinò Graziano Grugni Danilo Fintini Sara Osimani Letizia Ragusa Michele Sacco Lorenzo Iughetti Luisa De Sanctis Adriana Franzese Malgorzata Gabriela Wasniewska Maria Felicia Faienza Maurizio Delvecchio Concetta Esposito Giuliana Valerio |
| author_sort | Maria Rosaria Licenziati |
| collection | DOAJ |
| description | Background/ObjectivesThe present study aimed to validate the Italian version of the Hyperphagia Questionnaire (HQ), a 11-items questionnaire developed to assess hyperphagia in individuals with Prader-Willi syndrome (PWS). This is a complex neurodevelopmental disorder characterized by endocrine dysfunction, hypotonia, intellectual disability, psychiatric disorders and obesity.MethodsParents of 219 individuals with PWS (age range 3–54 years; Mage = 17.90; 108 Males), recruited in 12 hospitals in Italy responded to HQ during routine visits. In function of the level of analyses the sample was divided into two subgroups (<18> years) or into four age-subgroups (2.5–4.5; 4.5–8; 8–18; >18 years) corresponding to different clinical stages.ResultsConfirmatory factor analysis (CFA) confirmed the three hyperphagic subdimensions of the original structure (behavior, drive, and severity), but one item was dropped out, reducing the final version to 10 items. Using multi-group CFA, HQ showed satisfactory indexes of measurement invariance by age. Good indexes of internal consistency (Cronbach's alpha and McDonald's Omega coefficients) were found for each subdimension. The three hyperphagia subdimensions positively converged with other food-related measures: emotional overeating, food enjoyment, food responsiveness, and satiety responsiveness. A significant increase of all hyperphagic subdimensions was found across age groups. Higher hyperphagic levels were found in participants with higher body mass index. Hyperphagic drive differently increased in function of the interaction between age and underlying genetic mechanisms.ConclusionThe Italian version of the HQ is a psychometrically valid and reliable instrument for assessing hyperphagia in individuals with PWS. This tool may prove useful to evaluate the efficacy of pharmacologic and rehabilitative treatments. |
| first_indexed | 2024-12-23T00:26:55Z |
| format | Article |
| id | doaj.art-cad0e85e5de04908a6bf30f4e9dd6db5 |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-12-23T00:26:55Z |
| publishDate | 2022-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-cad0e85e5de04908a6bf30f4e9dd6db52022-12-21T18:07:05ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602022-02-011010.3389/fped.2022.829486829486The Hyperphagia Questionnaire: Insights From a Multicentric Validation Study in Individuals With Prader Willi SyndromeMaria Rosaria Licenziati0Dario Bacchini1Antonino Crinò2Graziano Grugni3Danilo Fintini4Sara Osimani5Letizia Ragusa6Michele Sacco7Lorenzo Iughetti8Luisa De Sanctis9Adriana Franzese10Malgorzata Gabriela Wasniewska11Maria Felicia Faienza12Maurizio Delvecchio13Concetta Esposito14Giuliana Valerio15Department of Neurosciences, Obesity and Endocrine Disease Unit, Santobono-Pausilipon Childrens Hospital, Naples, ItalyDepartment of Humanistic Studies, University of Naples “Federico II”, Naples, ItalyReference Center for Prader-Willi Syndrome, Research Institute, Bambino Gesù Hospital, Rome, ItalyDepartment of Auxology, Istituto di Ricerca e Cura a Carattere Scientifico Istituto Auxologico Italiano, Verbania, ItalyReference Center for Prader-Willi Syndrome, Research Institute, Bambino Gesù Hospital, Rome, ItalyDepartment of Pediatrics, Scientific Institute San Raffaele, Milan, ItalyOasi Research Institute-IRCCS, Troina, ItalyPediatric Unit Scientific Institute “Casa Sollievo Della Sofferenza” San Giovanni Rotondo (FG), San Giovanni Rotondo, ItalyPediatric Unit, Department of Medical and Surgical Sciences for Mothers, Children and Adults, University of Modena and Reggio Emilia, Modena, ItalyDepartment of Public Health and Pediatric Sciences, University of Torino, Turin, Italy0Department of Traslational Sciences, University of Naples Federico II, Naples, Italy1Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy2Department of Biomedical Sciences and Human Oncology, Pediatric Unit, University of Bari “Aldo Moro”, Bari, Italy3Metabolic Disorders and Genetics Unit, “Giovanni XXIII” Children's Hospital, Azienda Ospedaliera Universitaria (A.O.U.) Policlinico di Bari, Bari, ItalyDepartment of Humanistic Studies, University of Naples “Federico II”, Naples, Italy4Department of Movement Sciences and Wellbeing, Parthenope University of Naples, Naples, ItalyBackground/ObjectivesThe present study aimed to validate the Italian version of the Hyperphagia Questionnaire (HQ), a 11-items questionnaire developed to assess hyperphagia in individuals with Prader-Willi syndrome (PWS). This is a complex neurodevelopmental disorder characterized by endocrine dysfunction, hypotonia, intellectual disability, psychiatric disorders and obesity.MethodsParents of 219 individuals with PWS (age range 3–54 years; Mage = 17.90; 108 Males), recruited in 12 hospitals in Italy responded to HQ during routine visits. In function of the level of analyses the sample was divided into two subgroups (<18> years) or into four age-subgroups (2.5–4.5; 4.5–8; 8–18; >18 years) corresponding to different clinical stages.ResultsConfirmatory factor analysis (CFA) confirmed the three hyperphagic subdimensions of the original structure (behavior, drive, and severity), but one item was dropped out, reducing the final version to 10 items. Using multi-group CFA, HQ showed satisfactory indexes of measurement invariance by age. Good indexes of internal consistency (Cronbach's alpha and McDonald's Omega coefficients) were found for each subdimension. The three hyperphagia subdimensions positively converged with other food-related measures: emotional overeating, food enjoyment, food responsiveness, and satiety responsiveness. A significant increase of all hyperphagic subdimensions was found across age groups. Higher hyperphagic levels were found in participants with higher body mass index. Hyperphagic drive differently increased in function of the interaction between age and underlying genetic mechanisms.ConclusionThe Italian version of the HQ is a psychometrically valid and reliable instrument for assessing hyperphagia in individuals with PWS. This tool may prove useful to evaluate the efficacy of pharmacologic and rehabilitative treatments.https://www.frontiersin.org/articles/10.3389/fped.2022.829486/fullhyperphagiaPrader-Willi syndromemulticentric studyweight statusGenetic Obesityassessment |
| spellingShingle | Maria Rosaria Licenziati Dario Bacchini Antonino Crinò Graziano Grugni Danilo Fintini Sara Osimani Letizia Ragusa Michele Sacco Lorenzo Iughetti Luisa De Sanctis Adriana Franzese Malgorzata Gabriela Wasniewska Maria Felicia Faienza Maurizio Delvecchio Concetta Esposito Giuliana Valerio The Hyperphagia Questionnaire: Insights From a Multicentric Validation Study in Individuals With Prader Willi Syndrome Frontiers in Pediatrics hyperphagia Prader-Willi syndrome multicentric study weight status Genetic Obesity assessment |
| title | The Hyperphagia Questionnaire: Insights From a Multicentric Validation Study in Individuals With Prader Willi Syndrome |
| title_full | The Hyperphagia Questionnaire: Insights From a Multicentric Validation Study in Individuals With Prader Willi Syndrome |
| title_fullStr | The Hyperphagia Questionnaire: Insights From a Multicentric Validation Study in Individuals With Prader Willi Syndrome |
| title_full_unstemmed | The Hyperphagia Questionnaire: Insights From a Multicentric Validation Study in Individuals With Prader Willi Syndrome |
| title_short | The Hyperphagia Questionnaire: Insights From a Multicentric Validation Study in Individuals With Prader Willi Syndrome |
| title_sort | hyperphagia questionnaire insights from a multicentric validation study in individuals with prader willi syndrome |
| topic | hyperphagia Prader-Willi syndrome multicentric study weight status Genetic Obesity assessment |
| url | https://www.frontiersin.org/articles/10.3389/fped.2022.829486/full |
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