Tumor Microenvironment before and after Chemoradiation in Locally Advanced Rectal Cancer: Beyond PD-L1

Tumor Microenvironment before and after Chemoradiation in Locally Advanced Rectal Cancer: Beyond PD-L1

Background: In locally advanced rectal cancer treatment, neoadjuvant concurrent chemoradiation therapy (cCRT) is the standard of care. The tumor microenvironment (TME) is a complex entity comprising of tumor cells, immune cells and surrounding stroma and is closely associated with tumor growth and s...

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Bibliographic Details
Main Authors: Pritam Tayshetye, Andrew J. Friday, Ashten N. Omstead, Tanvi Verma, Stacey Miller, Ping Zheng, Prashant Jani, Ali Zaidi, Gene Finley
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
rectal cancer
chemoradiation
tumor microenvironment
neoadjuvant
biomarker
immunotherapy
Online Access:https://www.mdpi.com/2072-6694/15/1/276

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