Gliovascular and cytokine interactions modulate brain endothelial barrier <it>in vitro</it>

Gliovascular and cytokine interactions modulate brain endothelial barrier <it>in vitro</it>

<p>Abstract</p> <p>The glio-vascular unit (G-unit) plays a prominent role in maintaining homeostasis of the blood-brain barrier (BBB) and disturbances in cells forming this unit may seriously dysregulate BBB. The direct and indirect effects of cytokines on cellular components of th...

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Bibliographic Details
Main Authors: Chaitanya Ganta V, Cromer Walter E, Wells Shannon R, Jennings Merilyn H, Couraud P Olivier, Romero Ignacio A, Weksler Babette, Erdreich-Epstein Anat, Mathis J Michael, Minagar Alireza, Alexander J Steven
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Journal of Neuroinflammation
Subjects:
TNF-α
IL-1β
IFN-γ
Brain endothelium
Astrocytes
Co-culture
Mono-Culture
Online Access:http://www.jneuroinflammation.com/content/8/1/162

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