Epidemiology of gout in Hong Kong: a population-based study from 2006 to 2016
Abstract Objective To determine the incidence and prevalence of gout in the general population and the utilisation of urate-lowering therapy (ULT) among patients with gout in Hong Kong. Methods A total of 2,741,862 subjects who attended any outpatient clinics or accident and emergency department (wi...
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| Format: | Article |
| Language: | English |
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BMC
2020-09-01
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| Series: | Arthritis Research & Therapy |
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| Online Access: | http://link.springer.com/article/10.1186/s13075-020-02299-5 |
| _version_ | 1818304063854346240 |
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| author | Man Fung Tsoi Man Ho Chung Bernard Man Yung Cheung Chak Sing Lau Tommy Tsang Cheung |
| author_facet | Man Fung Tsoi Man Ho Chung Bernard Man Yung Cheung Chak Sing Lau Tommy Tsang Cheung |
| author_sort | Man Fung Tsoi |
| collection | DOAJ |
| description | Abstract Objective To determine the incidence and prevalence of gout in the general population and the utilisation of urate-lowering therapy (ULT) among patients with gout in Hong Kong. Methods A total of 2,741,862 subjects who attended any outpatient clinics or accident and emergency department (with or without hospitalisation) in 2005 and did not die before 2006 were identified from the Clinical Data Analysis and Reporting System (CDARS) of the Hospital Authority in Hong Kong. All subjects were followed until the end of 2016 or death. Demographics, diagnosis of gout, serum urate levels, and ULT prescriptions were retrieved from CDARS. Gout was defined by the diagnosis codes in CDARS. The serum urate levels achieved after prescribing ULT were the means of all serum urate levels measured 6 months after prescriptions. Results were analysed by R version 3.3.3 with package ‘prevalence’ version 0.4.0. Results The crude incidence of gout increased from 113.05/100,000 person-years (PY) in 2006 to 211.62/100,000 PY in 2016. The crude prevalence of gout increased from 1.56% in 2006 to 2.92% in 2016. Only 25.55% of patients with gout were prescribed ULT in 2016. 35.8% of patients treated with ULT were able to achieve the target serum urate level of < 6 mg/dL. Conclusions Population ageing as well as other risk factors contributed to an increase in the incidence and prevalence of gout in Hong Kong. In 2016, the crude prevalence of gout in Hong Kong was comparable to that in many western countries. However, only one in four patients with gout in Hong Kong was prescribed ULT. |
| first_indexed | 2024-12-13T06:04:45Z |
| format | Article |
| id | doaj.art-cadc2ed8d32c4002a354eb0c11487775 |
| institution | Directory Open Access Journal |
| issn | 1478-6362 |
| language | English |
| last_indexed | 2024-12-13T06:04:45Z |
| publishDate | 2020-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Arthritis Research & Therapy |
| spelling | doaj.art-cadc2ed8d32c4002a354eb0c114877752022-12-21T23:57:14ZengBMCArthritis Research & Therapy1478-63622020-09-012211910.1186/s13075-020-02299-5Epidemiology of gout in Hong Kong: a population-based study from 2006 to 2016Man Fung Tsoi0Man Ho Chung1Bernard Man Yung Cheung2Chak Sing Lau3Tommy Tsang Cheung4Department of Medicine, The University of Hong KongDepartment of Medicine, Queen Mary HospitalDepartment of Medicine, The University of Hong KongDepartment of Medicine, The University of Hong KongDepartment of Medicine, The University of Hong KongAbstract Objective To determine the incidence and prevalence of gout in the general population and the utilisation of urate-lowering therapy (ULT) among patients with gout in Hong Kong. Methods A total of 2,741,862 subjects who attended any outpatient clinics or accident and emergency department (with or without hospitalisation) in 2005 and did not die before 2006 were identified from the Clinical Data Analysis and Reporting System (CDARS) of the Hospital Authority in Hong Kong. All subjects were followed until the end of 2016 or death. Demographics, diagnosis of gout, serum urate levels, and ULT prescriptions were retrieved from CDARS. Gout was defined by the diagnosis codes in CDARS. The serum urate levels achieved after prescribing ULT were the means of all serum urate levels measured 6 months after prescriptions. Results were analysed by R version 3.3.3 with package ‘prevalence’ version 0.4.0. Results The crude incidence of gout increased from 113.05/100,000 person-years (PY) in 2006 to 211.62/100,000 PY in 2016. The crude prevalence of gout increased from 1.56% in 2006 to 2.92% in 2016. Only 25.55% of patients with gout were prescribed ULT in 2016. 35.8% of patients treated with ULT were able to achieve the target serum urate level of < 6 mg/dL. Conclusions Population ageing as well as other risk factors contributed to an increase in the incidence and prevalence of gout in Hong Kong. In 2016, the crude prevalence of gout in Hong Kong was comparable to that in many western countries. However, only one in four patients with gout in Hong Kong was prescribed ULT.http://link.springer.com/article/10.1186/s13075-020-02299-5GoutHong KongEpidemiologyUrate-lowering therapy |
| spellingShingle | Man Fung Tsoi Man Ho Chung Bernard Man Yung Cheung Chak Sing Lau Tommy Tsang Cheung Epidemiology of gout in Hong Kong: a population-based study from 2006 to 2016 Arthritis Research & Therapy Gout Hong Kong Epidemiology Urate-lowering therapy |
| title | Epidemiology of gout in Hong Kong: a population-based study from 2006 to 2016 |
| title_full | Epidemiology of gout in Hong Kong: a population-based study from 2006 to 2016 |
| title_fullStr | Epidemiology of gout in Hong Kong: a population-based study from 2006 to 2016 |
| title_full_unstemmed | Epidemiology of gout in Hong Kong: a population-based study from 2006 to 2016 |
| title_short | Epidemiology of gout in Hong Kong: a population-based study from 2006 to 2016 |
| title_sort | epidemiology of gout in hong kong a population based study from 2006 to 2016 |
| topic | Gout Hong Kong Epidemiology Urate-lowering therapy |
| url | http://link.springer.com/article/10.1186/s13075-020-02299-5 |
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