Parenterally Administered Porcine Epidemic Diarrhea Virus-Like Particle-Based Vaccine Formulated with CCL25/28 Chemokines Induces Systemic and Mucosal Immune Protectivity in Pigs

Parenterally Administered Porcine Epidemic Diarrhea Virus-Like Particle-Based Vaccine Formulated with CCL25/28 Chemokines Induces Systemic and Mucosal Immune Protectivity in Pigs

Generation of a safe, economical, and effective vaccine capable of inducing mucosal immunity is critical for the development of vaccines against enteric viral diseases. In the current study, virus-like particles (VLPs) containing the spike (S), membrane (M), and envelope (E) structural proteins of p...

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Bibliographic Details
Main Authors: Chin-Wei Hsu, Ming-Hao Chang, Hui-Wen Chang, Tzong-Yuan Wu, Yen-Chen Chang
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Viruses
Subjects:
porcine epidemic diarrhea virus
VLP
chemokines
pig
vaccine
Online Access:https://www.mdpi.com/1999-4915/12/10/1122

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