Clinical, epidemiological, and histopathological aspects of breast cancer in female dogs at Federal Rural University of Rio de Janeiro Veterinary Hospital
This study aimed to evaluate the clinical, epidemiological, and histopathological aspects of canine breast tumors at the Federal Rural University of Rio de Janeiro Veterinary Hospital (VH-UFRRJ) between April 2017 and October 2018. The study included 137 female canine dogs with mammary neoplasia who...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade de Medicina Veterinária do Estado do Rio de Janeiro
2022-09-01
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| Series: | Brazilian Journal of Veterinary Medicine |
| Subjects: | |
| Online Access: | https://bjvm.org.br/BJVM/article/view/1258 |
| _version_ | 1797831844073308160 |
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| author | Lucinéia Costa Oliveira Maria Eduarda dos Santos Lopes Fernandes Anna Julia Rodrigues Peixoto Felipe Farias Pereira da Camara Barros Cássia Maria Molinaro Coelho Vivian de Assunção Vivian de Assunção Saulo Andrade Caldas |
| author_facet | Lucinéia Costa Oliveira Maria Eduarda dos Santos Lopes Fernandes Anna Julia Rodrigues Peixoto Felipe Farias Pereira da Camara Barros Cássia Maria Molinaro Coelho Vivian de Assunção Vivian de Assunção Saulo Andrade Caldas |
| author_sort | Lucinéia Costa Oliveira |
| collection | DOAJ |
| description | This study aimed to evaluate the clinical, epidemiological, and histopathological aspects of canine breast tumors at the Federal Rural University of Rio de Janeiro Veterinary Hospital (VH-UFRRJ) between April 2017 and October 2018. The study included 137 female canine dogs with mammary neoplasia who underwent a mastectomy. The animals were evaluated using a standard form that guided anamnesis and physical examination to assess the tumor’s epidemiology, development, evolution, treatment choice, and disease prognosis. Furthermore, laboratory and imaging tests were performed on the animals to search for changes that suggested metastasis. The average age of the female dogs was 10 years, and mixed-breed dogs (33%) were the most affected, followed by poodles (21%). The inguinal (79%) and caudal abdominal (64%) breasts were the most affected. Approximately 26% of the animals were castrated, 32% had already reproduced throughout their lives, 30% had pseudocyesis, and only 8% used contraceptive methods. The majority were classified as stage I (33%) and stage III (39%) according to the Tumor-Node-Metastasis (TNM) Classification System of Malignant Tumors. In 95 female dogs, 191 nodules were histopathologically evaluated, and 62% of these animals had at least one malignant tumor. Statistically, there was a direct association between tumor size and malignancy. However, other associations, such as age at diagnosis and the degree of malignancy, were not confirmed. Therefore, it can be concluded that tumor size is an important prognostic factor, with tumors >3 cm having an approximately 70% chance of being malignant. |
| first_indexed | 2024-04-09T13:58:13Z |
| format | Article |
| id | doaj.art-cae5cc8196ac4d50a6f4bc27cf1a1e2e |
| institution | Directory Open Access Journal |
| issn | 0100-2430 2527-2179 |
| language | English |
| last_indexed | 2024-04-09T13:58:13Z |
| publishDate | 2022-09-01 |
| publisher | Sociedade de Medicina Veterinária do Estado do Rio de Janeiro |
| record_format | Article |
| series | Brazilian Journal of Veterinary Medicine |
| spelling | doaj.art-cae5cc8196ac4d50a6f4bc27cf1a1e2e2023-05-07T12:41:28ZengSociedade de Medicina Veterinária do Estado do Rio de JaneiroBrazilian Journal of Veterinary Medicine0100-24302527-21792022-09-0144e000722e00072210.29374/2527-2179.bjvm0007221146Clinical, epidemiological, and histopathological aspects of breast cancer in female dogs at Federal Rural University of Rio de Janeiro Veterinary HospitalLucinéia Costa Oliveira0https://orcid.org/0000-0001-7445-6746Maria Eduarda dos Santos Lopes Fernandes1https://orcid.org/0000-0003-1414-2475Anna Julia Rodrigues Peixoto2https://orcid.org/0000-0002-4861-7726Felipe Farias Pereira da Camara Barros3https://orcid.org/0000-0003-2071-6930Cássia Maria Molinaro Coelho4https://orcid.org/0000-0003-1205-8413Vivian de Assunção Vivian de Assunção5https://orcid.org/0000-0002-4034-9675Saulo Andrade Caldas6https://orcid.org/0000-0002-3413-7924Veterinarian, MSc., Programa de Pós-graduação em Medicina Veterinária, Departamento de Medicina e Cirurgia Veterinária (DMCV), Instituto de Veterinária (IV), Universidade Federal Rural do Rio de Janeiro (UFRRJ), campus Seropédica – RJ, Brazil Veterinarian, MSc., PPGMV, DMCV,IV, UFRRJ, campus Seropédica – RJ, Brazil Veterinarian, MSc., PPGMV, DMCV, IV, UFRRJ, campus Seropédica – RJ, BrazilVeterinarian, DSc., DMCV, IV, UFRRJ, campus Seropédica – RJ, Brazil Veterinarian, DSc., DMCV, IV, UFRRJ, campus Seropédica – RJ, Brazil Veterinarian, DSc., Departamento de Epidemiologia e Saúde Pública, IV, UFRRJ, campus Seropédica – RJ, BrazilVeterinarian, DSc., DMCV, IV, UFRRJ, campus Seropédica – RJ, Brazil This study aimed to evaluate the clinical, epidemiological, and histopathological aspects of canine breast tumors at the Federal Rural University of Rio de Janeiro Veterinary Hospital (VH-UFRRJ) between April 2017 and October 2018. The study included 137 female canine dogs with mammary neoplasia who underwent a mastectomy. The animals were evaluated using a standard form that guided anamnesis and physical examination to assess the tumor’s epidemiology, development, evolution, treatment choice, and disease prognosis. Furthermore, laboratory and imaging tests were performed on the animals to search for changes that suggested metastasis. The average age of the female dogs was 10 years, and mixed-breed dogs (33%) were the most affected, followed by poodles (21%). The inguinal (79%) and caudal abdominal (64%) breasts were the most affected. Approximately 26% of the animals were castrated, 32% had already reproduced throughout their lives, 30% had pseudocyesis, and only 8% used contraceptive methods. The majority were classified as stage I (33%) and stage III (39%) according to the Tumor-Node-Metastasis (TNM) Classification System of Malignant Tumors. In 95 female dogs, 191 nodules were histopathologically evaluated, and 62% of these animals had at least one malignant tumor. Statistically, there was a direct association between tumor size and malignancy. However, other associations, such as age at diagnosis and the degree of malignancy, were not confirmed. Therefore, it can be concluded that tumor size is an important prognostic factor, with tumors >3 cm having an approximately 70% chance of being malignant.https://bjvm.org.br/BJVM/article/view/1258dog, malignancy, mastectomy. |
| spellingShingle | Lucinéia Costa Oliveira Maria Eduarda dos Santos Lopes Fernandes Anna Julia Rodrigues Peixoto Felipe Farias Pereira da Camara Barros Cássia Maria Molinaro Coelho Vivian de Assunção Vivian de Assunção Saulo Andrade Caldas Clinical, epidemiological, and histopathological aspects of breast cancer in female dogs at Federal Rural University of Rio de Janeiro Veterinary Hospital Brazilian Journal of Veterinary Medicine dog, malignancy, mastectomy. |
| title | Clinical, epidemiological, and histopathological aspects of breast cancer in female dogs at Federal Rural University of Rio de Janeiro Veterinary Hospital |
| title_full | Clinical, epidemiological, and histopathological aspects of breast cancer in female dogs at Federal Rural University of Rio de Janeiro Veterinary Hospital |
| title_fullStr | Clinical, epidemiological, and histopathological aspects of breast cancer in female dogs at Federal Rural University of Rio de Janeiro Veterinary Hospital |
| title_full_unstemmed | Clinical, epidemiological, and histopathological aspects of breast cancer in female dogs at Federal Rural University of Rio de Janeiro Veterinary Hospital |
| title_short | Clinical, epidemiological, and histopathological aspects of breast cancer in female dogs at Federal Rural University of Rio de Janeiro Veterinary Hospital |
| title_sort | clinical epidemiological and histopathological aspects of breast cancer in female dogs at federal rural university of rio de janeiro veterinary hospital |
| topic | dog, malignancy, mastectomy. |
| url | https://bjvm.org.br/BJVM/article/view/1258 |
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