Systemic aspirin and systemic vitamin E in senile cataracts : cataract V
We undertook a prospective study in senile cataract patients using systemic aspirin and systemic vitamin E. Vitamin E treated eyes did show less progression of PSC opacities extent and less new nuclear opacities during the follow-up, but overall vitamin E treated eyes did no better than the control...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
1989-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=1989;volume=37;issue=3;spage=134;epage=141;aulast=Sharma |
| _version_ | 1818901540206804992 |
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| author | Sharma Y Vajpayee R Bhatnagar R Mohan Madan Azad R Kumar Mukesh Nath Ram |
| author_facet | Sharma Y Vajpayee R Bhatnagar R Mohan Madan Azad R Kumar Mukesh Nath Ram |
| author_sort | Sharma Y |
| collection | DOAJ |
| description | We undertook a prospective study in senile cataract patients using systemic aspirin and systemic vitamin E. Vitamin E treated eyes did show less progression of PSC opacities extent and less new nuclear opacities during the follow-up, but overall vitamin E treated eyes did no better than the control group eyes. More eyes in systemic aspirin treated group maintained the initial vision and loss of vision in the aspirin group was also less marked. Aspirin also caused a significant less mean increase in cortical opacity extent, nuclear/opacity and density and PSC opacity extent and density as well as in ophthalmoscopically graded opacity extent and density. We suggest that aspirin is a potential drug which should be further evaluated in large double blind photodocumentated studies. The present data does not justify the recommendation that aspirin be prescribed for slowing down cataract progression. This must await large studies and confirmation. |
| first_indexed | 2024-12-19T20:21:22Z |
| format | Article |
| id | doaj.art-cae621dc12ee4d53aa1c531775b0cf33 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 |
| language | English |
| last_indexed | 2024-12-19T20:21:22Z |
| publishDate | 1989-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-cae621dc12ee4d53aa1c531775b0cf332022-12-21T20:07:00ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381989-01-01373134141Systemic aspirin and systemic vitamin E in senile cataracts : cataract VSharma YVajpayee RBhatnagar RMohan MadanAzad RKumar MukeshNath RamWe undertook a prospective study in senile cataract patients using systemic aspirin and systemic vitamin E. Vitamin E treated eyes did show less progression of PSC opacities extent and less new nuclear opacities during the follow-up, but overall vitamin E treated eyes did no better than the control group eyes. More eyes in systemic aspirin treated group maintained the initial vision and loss of vision in the aspirin group was also less marked. Aspirin also caused a significant less mean increase in cortical opacity extent, nuclear/opacity and density and PSC opacity extent and density as well as in ophthalmoscopically graded opacity extent and density. We suggest that aspirin is a potential drug which should be further evaluated in large double blind photodocumentated studies. The present data does not justify the recommendation that aspirin be prescribed for slowing down cataract progression. This must await large studies and confirmation.http://www.ijo.in/article.asp?issn=0301-4738;year=1989;volume=37;issue=3;spage=134;epage=141;aulast=SharmaAspirinVitamin EMedical therapy of cataracts |
| spellingShingle | Sharma Y Vajpayee R Bhatnagar R Mohan Madan Azad R Kumar Mukesh Nath Ram Systemic aspirin and systemic vitamin E in senile cataracts : cataract V Indian Journal of Ophthalmology Aspirin Vitamin E Medical therapy of cataracts |
| title | Systemic aspirin and systemic vitamin E in senile cataracts : cataract V |
| title_full | Systemic aspirin and systemic vitamin E in senile cataracts : cataract V |
| title_fullStr | Systemic aspirin and systemic vitamin E in senile cataracts : cataract V |
| title_full_unstemmed | Systemic aspirin and systemic vitamin E in senile cataracts : cataract V |
| title_short | Systemic aspirin and systemic vitamin E in senile cataracts : cataract V |
| title_sort | systemic aspirin and systemic vitamin e in senile cataracts cataract v |
| topic | Aspirin Vitamin E Medical therapy of cataracts |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=1989;volume=37;issue=3;spage=134;epage=141;aulast=Sharma |
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