Correlation of androgen receptor with ultrasound, clinicopathological features and clinical outcomes in breast cancer
Key points In terms of clinicopathology, the probability of AR expression in different subtypes of breast cancer was various, and the positive expression of AR was associated with lower histological grade and lower Ki-67 level. In terms of ultrasound, the positive expression of AR was associated wit...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2023-03-01
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| Series: | Insights into Imaging |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13244-023-01387-9 |
| _version_ | 1827983948943196160 |
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| author | Xudong Zhang Hao Cui Nana Hu Peng Han Wei Fan Panting Wang Xiaoxuan Zuo Dantong Zhao He Huang Shuo Li Hanqing Kong Fuhui Peng Jiawei Tian Lei Zhang |
| author_facet | Xudong Zhang Hao Cui Nana Hu Peng Han Wei Fan Panting Wang Xiaoxuan Zuo Dantong Zhao He Huang Shuo Li Hanqing Kong Fuhui Peng Jiawei Tian Lei Zhang |
| author_sort | Xudong Zhang |
| collection | DOAJ |
| description | Key points In terms of clinicopathology, the probability of AR expression in different subtypes of breast cancer was various, and the positive expression of AR was associated with lower histological grade and lower Ki-67 level. In terms of ultrasound, the positive expression of AR was associated with unsmooth margin, posterior acoustic shadowing and stiffer on strain elastography, and AR + and AR– tumors performed differently when analyzed separately according to different molecular subtypes. The positive expression of AR could be a sign of a better prognosis in breast cancer. |
| first_indexed | 2024-04-09T22:53:15Z |
| format | Article |
| id | doaj.art-cae7ad329eb84c72ba423be7599d6e8a |
| institution | Directory Open Access Journal |
| issn | 1869-4101 |
| language | English |
| last_indexed | 2024-04-09T22:53:15Z |
| publishDate | 2023-03-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Insights into Imaging |
| spelling | doaj.art-cae7ad329eb84c72ba423be7599d6e8a2023-03-22T11:31:55ZengSpringerOpenInsights into Imaging1869-41012023-03-0114111410.1186/s13244-023-01387-9Correlation of androgen receptor with ultrasound, clinicopathological features and clinical outcomes in breast cancerXudong Zhang0Hao Cui1Nana Hu2Peng Han3Wei Fan4Panting Wang5Xiaoxuan Zuo6Dantong Zhao7He Huang8Shuo Li9Hanqing Kong10Fuhui Peng11Jiawei Tian12Lei Zhang13Department of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Clinical Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Clinical Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityKey points In terms of clinicopathology, the probability of AR expression in different subtypes of breast cancer was various, and the positive expression of AR was associated with lower histological grade and lower Ki-67 level. In terms of ultrasound, the positive expression of AR was associated with unsmooth margin, posterior acoustic shadowing and stiffer on strain elastography, and AR + and AR– tumors performed differently when analyzed separately according to different molecular subtypes. The positive expression of AR could be a sign of a better prognosis in breast cancer.https://doi.org/10.1186/s13244-023-01387-9Breast cancerAndrogen receptorUltrasoundNomogramPrognosis |
| spellingShingle | Xudong Zhang Hao Cui Nana Hu Peng Han Wei Fan Panting Wang Xiaoxuan Zuo Dantong Zhao He Huang Shuo Li Hanqing Kong Fuhui Peng Jiawei Tian Lei Zhang Correlation of androgen receptor with ultrasound, clinicopathological features and clinical outcomes in breast cancer Insights into Imaging Breast cancer Androgen receptor Ultrasound Nomogram Prognosis |
| title | Correlation of androgen receptor with ultrasound, clinicopathological features and clinical outcomes in breast cancer |
| title_full | Correlation of androgen receptor with ultrasound, clinicopathological features and clinical outcomes in breast cancer |
| title_fullStr | Correlation of androgen receptor with ultrasound, clinicopathological features and clinical outcomes in breast cancer |
| title_full_unstemmed | Correlation of androgen receptor with ultrasound, clinicopathological features and clinical outcomes in breast cancer |
| title_short | Correlation of androgen receptor with ultrasound, clinicopathological features and clinical outcomes in breast cancer |
| title_sort | correlation of androgen receptor with ultrasound clinicopathological features and clinical outcomes in breast cancer |
| topic | Breast cancer Androgen receptor Ultrasound Nomogram Prognosis |
| url | https://doi.org/10.1186/s13244-023-01387-9 |
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