Chronological changes of incidence and prognosis of children with asymptomatic congenital cytomegalovirus infection in Sapporo, Japan
<p>Abstract</p> <p>Background</p> <p>Chronological changes of the incidence of congenital cytomegalovirus (CMV) infection and the longitudinal prognosis in children with asymptomatic congenital infection were investigated.</p> <p>Methods</p> <p>C...
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| Format: | Article |
| Language: | English |
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BMC
2004-07-01
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| Series: | BMC Infectious Diseases |
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| Online Access: | http://www.biomedcentral.com/1471-2334/4/22 |
| _version_ | 1818276669963632640 |
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| author | Fujikawa Tomoko Numazaki Kei |
| author_facet | Fujikawa Tomoko Numazaki Kei |
| author_sort | Fujikawa Tomoko |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Chronological changes of the incidence of congenital cytomegalovirus (CMV) infection and the longitudinal prognosis in children with asymptomatic congenital infection were investigated.</p> <p>Methods</p> <p>Congenital CMV infection, as demonstrated by isolation of the virus within the first week of life, was diagnosed in infants born in Sapporo, Japan, during the 26-year period between 1977 and 2002.</p> <p>Results</p> <p>Congenital infection was diagnosed in 37 (0.31%) of 11,938 infants. Thirty-two infants were (86.5%) asymptomatic and 5 (13.5%) were symptomatic at birth.</p> <p>Conclusions</p> <p>Although a decrease in the total incidence of congenital CMV infection has been seen in recent years, screening of congenital infection at birth seems to be necessary to detect late-onset neurodevelopmental sequelae.</p> |
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| format | Article |
| id | doaj.art-caebc83db97c4c03889bb097ca60281a |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-12T22:49:20Z |
| publishDate | 2004-07-01 |
| publisher | BMC |
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| series | BMC Infectious Diseases |
| spelling | doaj.art-caebc83db97c4c03889bb097ca60281a2022-12-22T00:09:07ZengBMCBMC Infectious Diseases1471-23342004-07-01412210.1186/1471-2334-4-22Chronological changes of incidence and prognosis of children with asymptomatic congenital cytomegalovirus infection in Sapporo, JapanFujikawa TomokoNumazaki Kei<p>Abstract</p> <p>Background</p> <p>Chronological changes of the incidence of congenital cytomegalovirus (CMV) infection and the longitudinal prognosis in children with asymptomatic congenital infection were investigated.</p> <p>Methods</p> <p>Congenital CMV infection, as demonstrated by isolation of the virus within the first week of life, was diagnosed in infants born in Sapporo, Japan, during the 26-year period between 1977 and 2002.</p> <p>Results</p> <p>Congenital infection was diagnosed in 37 (0.31%) of 11,938 infants. Thirty-two infants were (86.5%) asymptomatic and 5 (13.5%) were symptomatic at birth.</p> <p>Conclusions</p> <p>Although a decrease in the total incidence of congenital CMV infection has been seen in recent years, screening of congenital infection at birth seems to be necessary to detect late-onset neurodevelopmental sequelae.</p>http://www.biomedcentral.com/1471-2334/4/22cytomegaloviruscongenital infectionsensorineural hearing lossintracellular cytokine |
| spellingShingle | Fujikawa Tomoko Numazaki Kei Chronological changes of incidence and prognosis of children with asymptomatic congenital cytomegalovirus infection in Sapporo, Japan BMC Infectious Diseases cytomegalovirus congenital infection sensorineural hearing loss intracellular cytokine |
| title | Chronological changes of incidence and prognosis of children with asymptomatic congenital cytomegalovirus infection in Sapporo, Japan |
| title_full | Chronological changes of incidence and prognosis of children with asymptomatic congenital cytomegalovirus infection in Sapporo, Japan |
| title_fullStr | Chronological changes of incidence and prognosis of children with asymptomatic congenital cytomegalovirus infection in Sapporo, Japan |
| title_full_unstemmed | Chronological changes of incidence and prognosis of children with asymptomatic congenital cytomegalovirus infection in Sapporo, Japan |
| title_short | Chronological changes of incidence and prognosis of children with asymptomatic congenital cytomegalovirus infection in Sapporo, Japan |
| title_sort | chronological changes of incidence and prognosis of children with asymptomatic congenital cytomegalovirus infection in sapporo japan |
| topic | cytomegalovirus congenital infection sensorineural hearing loss intracellular cytokine |
| url | http://www.biomedcentral.com/1471-2334/4/22 |
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