Targeting sTNF/TNFR1 Signaling as a New Therapeutic Strategy

Targeting sTNF/TNFR1 Signaling as a New Therapeutic Strategy

Deregulation of the tumor necrosis factor (TNF) plays an important role in the initiation and perpetuation of chronic inflammation and has been implicated in the development of various autoimmune diseases. Accordingly, TNF-inhibitors are successfully used for the treatment of several diseases, such...

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Bibliographic Details
Main Authors:	Roman Fischer, Roland E. Kontermann, Olaf Maier
Format:	Article
Language:	English
Published:	MDPI AG 2015-03-01
Series:	Antibodies
Subjects:	antibodies autoimmune diseases inflammation neurodegeneration TNF TNF receptors
Online Access:	http://www.mdpi.com/2073-4468/4/1/48

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