Clinical Utility of Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI) in Gastrointestinal Cancers

Anatomic imaging utilizing both CT (computed tomography) and MRI (magnetic resonance imaging) limits the assessment of cancer metastases in lymph nodes and distant organs while functional imaging like PET (positron emission tomography) scan has its limitation in spatial resolution capacity. Hybrid i...

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Main Authors: Robert Matthews, Minsig Choi
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Diagnostics
Subjects:
Online Access:http://www.mdpi.com/2075-4418/6/3/35
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author Robert Matthews
Minsig Choi
author_facet Robert Matthews
Minsig Choi
author_sort Robert Matthews
collection DOAJ
description Anatomic imaging utilizing both CT (computed tomography) and MRI (magnetic resonance imaging) limits the assessment of cancer metastases in lymph nodes and distant organs while functional imaging like PET (positron emission tomography) scan has its limitation in spatial resolution capacity. Hybrid imaging utilizing PET-CT and PET-MRI are novel imaging modalities that are changing the current landscape in cancer diagnosis, staging, and treatment response. MRI has shown to have higher sensitivity in soft tissue, head and neck pathology, and pelvic disease, as well as, detecting small metastases in the liver and bone compared to CT. Combining MRI with PET allows for detection of metastases that may have been missed with current imaging modalities. In this review, we will examine the clinical utility of FDG PET-MRI in the diagnosis and staging of gastrointestinal cancers with focus on esophageal, stomach, colorectal, and pancreatic cancers. We will also explore its role in treatment response and future directions associated with it.
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spelling doaj.art-caed2df187f149d5a5cae110531e9be22022-12-22T04:22:59ZengMDPI AGDiagnostics2075-44182016-09-01633510.3390/diagnostics6030035diagnostics6030035Clinical Utility of Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI) in Gastrointestinal CancersRobert Matthews0Minsig Choi1Department of Radiology, Stony Brook University Medical Center, Stony Brook, NY 11794, USADepartment of Medicine, Stony Brook University Medical Center, Stony Brook, NY 11794, USAAnatomic imaging utilizing both CT (computed tomography) and MRI (magnetic resonance imaging) limits the assessment of cancer metastases in lymph nodes and distant organs while functional imaging like PET (positron emission tomography) scan has its limitation in spatial resolution capacity. Hybrid imaging utilizing PET-CT and PET-MRI are novel imaging modalities that are changing the current landscape in cancer diagnosis, staging, and treatment response. MRI has shown to have higher sensitivity in soft tissue, head and neck pathology, and pelvic disease, as well as, detecting small metastases in the liver and bone compared to CT. Combining MRI with PET allows for detection of metastases that may have been missed with current imaging modalities. In this review, we will examine the clinical utility of FDG PET-MRI in the diagnosis and staging of gastrointestinal cancers with focus on esophageal, stomach, colorectal, and pancreatic cancers. We will also explore its role in treatment response and future directions associated with it.http://www.mdpi.com/2075-4418/6/3/35PET-MRIpositron emission tomographyfluorodeoxyglucosemagnetic resonance imagingcancer
spellingShingle Robert Matthews
Minsig Choi
Clinical Utility of Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI) in Gastrointestinal Cancers
Diagnostics
PET-MRI
positron emission tomography
fluorodeoxyglucose
magnetic resonance imaging
cancer
title Clinical Utility of Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI) in Gastrointestinal Cancers
title_full Clinical Utility of Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI) in Gastrointestinal Cancers
title_fullStr Clinical Utility of Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI) in Gastrointestinal Cancers
title_full_unstemmed Clinical Utility of Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI) in Gastrointestinal Cancers
title_short Clinical Utility of Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI) in Gastrointestinal Cancers
title_sort clinical utility of positron emission tomography magnetic resonance imaging pet mri in gastrointestinal cancers
topic PET-MRI
positron emission tomography
fluorodeoxyglucose
magnetic resonance imaging
cancer
url http://www.mdpi.com/2075-4418/6/3/35
work_keys_str_mv AT robertmatthews clinicalutilityofpositronemissiontomographymagneticresonanceimagingpetmriingastrointestinalcancers
AT minsigchoi clinicalutilityofpositronemissiontomographymagneticresonanceimagingpetmriingastrointestinalcancers