Corneal Adhesion Possesses the Characteristics of Solid and Membrane
Adhesion behavior usually occurs in corneas associated with clinical treatments. Physiologically, an intact natural cornea is inflated by intraocular pressure. Due to the inflation, the physiological cornea has a mechanical property likeness to membrane. This characteristic is ignored by the classic...
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| Format: | Article |
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MDPI AG
2022-08-01
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| Series: | Bioengineering |
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| Online Access: | https://www.mdpi.com/2306-5354/9/8/394 |
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| author | Jiajin Yang Qiaomei Ren Dong Zhao Zhipeng Gao Xiaona Li Rui He Weiyi Chen |
| author_facet | Jiajin Yang Qiaomei Ren Dong Zhao Zhipeng Gao Xiaona Li Rui He Weiyi Chen |
| author_sort | Jiajin Yang |
| collection | DOAJ |
| description | Adhesion behavior usually occurs in corneas associated with clinical treatments. Physiologically, an intact natural cornea is inflated by intraocular pressure. Due to the inflation, the physiological cornea has a mechanical property likeness to membrane. This characteristic is ignored by the classical theory used to analyze the adhesion behavior of soft solids, such as the Johnson–Kendall–Roberts (JKR) model. Performing the pull-off test, this work evidenced that the classical JKR solution was suitable for computing the corneal adhesion force corresponding to the submillimeter scale of contact. However, when the cornea was contacted at a millimeter scale, the JKR solutions were clearly smaller than the related experimental data. The reason was correlated with the membranous characteristic of the natural cornea was not considered in the JKR solid model. In this work, the modified JKR model was superimposed by the contribution from the surface tension related to the corneal inflation due to the intraocular pressure. It should be treated as a solid when the cornea is contacted at a submillimeter scale, whereas for the contact at a larger size, the characteristic of the membrane should be considered in analyzing the corneal adhesion. The modified JKR model successfully described the adhesion characteristics of the cornea from solid to membrane. |
| first_indexed | 2024-03-09T10:01:56Z |
| format | Article |
| id | doaj.art-caf03bc762a1462890bb733d0f62efc9 |
| institution | Directory Open Access Journal |
| issn | 2306-5354 |
| language | English |
| last_indexed | 2024-03-09T10:01:56Z |
| publishDate | 2022-08-01 |
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| series | Bioengineering |
| spelling | doaj.art-caf03bc762a1462890bb733d0f62efc92023-12-01T23:25:22ZengMDPI AGBioengineering2306-53542022-08-019839410.3390/bioengineering9080394Corneal Adhesion Possesses the Characteristics of Solid and MembraneJiajin Yang0Qiaomei Ren1Dong Zhao2Zhipeng Gao3Xiaona Li4Rui He5Weiyi Chen6Department of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030000, ChinaDepartment of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030000, ChinaDepartment of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030000, ChinaDepartment of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030000, ChinaDepartment of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030000, ChinaDepartment of Excimer Laser, Shanxi Medical University, Taiyuan 030000, ChinaDepartment of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030000, ChinaAdhesion behavior usually occurs in corneas associated with clinical treatments. Physiologically, an intact natural cornea is inflated by intraocular pressure. Due to the inflation, the physiological cornea has a mechanical property likeness to membrane. This characteristic is ignored by the classical theory used to analyze the adhesion behavior of soft solids, such as the Johnson–Kendall–Roberts (JKR) model. Performing the pull-off test, this work evidenced that the classical JKR solution was suitable for computing the corneal adhesion force corresponding to the submillimeter scale of contact. However, when the cornea was contacted at a millimeter scale, the JKR solutions were clearly smaller than the related experimental data. The reason was correlated with the membranous characteristic of the natural cornea was not considered in the JKR solid model. In this work, the modified JKR model was superimposed by the contribution from the surface tension related to the corneal inflation due to the intraocular pressure. It should be treated as a solid when the cornea is contacted at a submillimeter scale, whereas for the contact at a larger size, the characteristic of the membrane should be considered in analyzing the corneal adhesion. The modified JKR model successfully described the adhesion characteristics of the cornea from solid to membrane.https://www.mdpi.com/2306-5354/9/8/394biomechanicsophthalmologyJKR theoryadhesion behavior |
| spellingShingle | Jiajin Yang Qiaomei Ren Dong Zhao Zhipeng Gao Xiaona Li Rui He Weiyi Chen Corneal Adhesion Possesses the Characteristics of Solid and Membrane Bioengineering biomechanics ophthalmology JKR theory adhesion behavior |
| title | Corneal Adhesion Possesses the Characteristics of Solid and Membrane |
| title_full | Corneal Adhesion Possesses the Characteristics of Solid and Membrane |
| title_fullStr | Corneal Adhesion Possesses the Characteristics of Solid and Membrane |
| title_full_unstemmed | Corneal Adhesion Possesses the Characteristics of Solid and Membrane |
| title_short | Corneal Adhesion Possesses the Characteristics of Solid and Membrane |
| title_sort | corneal adhesion possesses the characteristics of solid and membrane |
| topic | biomechanics ophthalmology JKR theory adhesion behavior |
| url | https://www.mdpi.com/2306-5354/9/8/394 |
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