Benefits and Challenges of <i>Jatropha</i> Meal as Novel Biofeed for Animal Production
<i>Jatropha curcas</i> L. has gained importance as a source of seed oil for biodiesel production. The meal contained about 60% protein with a good balance of essential amino acids, containing various bioactive compounds, including saponins, phytic acids, trypsin inhibitors, lectins, phen...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-09-01
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| Series: | Veterinary Sciences |
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| Online Access: | https://www.mdpi.com/2306-7381/8/9/179 |
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| author | Ehsan Oskoueian Arshin Oskoueian Majid Shakeri Mohammad Faseleh Jahromi |
| author_facet | Ehsan Oskoueian Arshin Oskoueian Majid Shakeri Mohammad Faseleh Jahromi |
| author_sort | Ehsan Oskoueian |
| collection | DOAJ |
| description | <i>Jatropha curcas</i> L. has gained importance as a source of seed oil for biodiesel production. The meal contained about 60% protein with a good balance of essential amino acids, containing various bioactive compounds, including saponins, phytic acids, trypsin inhibitors, lectins, phenolics, and flavonoids, which render it as a potential biofeed for animal production. The <i>Jatropha</i> meal demonstrated various biological activities, including antioxidant, antibacterial, and anti-inflammatory effects which enhance its property as a bio-feed. The levels of these bioactive compounds in the seeds are dependent on the genotypes. The <i>J. curcas</i> possessed different varieties which are either toxic or non-toxic according to the presence of phorbol esters. The presence of phorbol esters in the meal confirmed the toxic variety of <i>Jatropha</i> resulting in the limited application of meal as a biofeed. The <i>Jatropha</i> meal devoid of phorbol esters could be applied as a biofeed in the animal production industry, and for the toxic varieties, various techniques such as physicochemical and biological treatments have been introduced to the industry to remove the phorbol esters from <i>Jatropha</i> meal. Several studies employing various cells and animals confirmed the toxicity of the phorbol esters. The molecular mechanism of action of phorbol esters is through up-regulation of PKC-β II gene, overexpression of down-stream proto-oncogenes resulted in inflammation and oxidative stress ending by apoptotic cell death. Despite the presence of valuable bioactive compounds in the <i>Jatropha</i> meal, its nutritional application is not recommended unless the phorbol esters are completely removed. |
| first_indexed | 2024-03-10T07:09:03Z |
| format | Article |
| id | doaj.art-caf0d65123644c85addbcc1647ce6e39 |
| institution | Directory Open Access Journal |
| issn | 2306-7381 |
| language | English |
| last_indexed | 2024-03-10T07:09:03Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Veterinary Sciences |
| spelling | doaj.art-caf0d65123644c85addbcc1647ce6e392023-11-22T15:35:47ZengMDPI AGVeterinary Sciences2306-73812021-09-018917910.3390/vetsci8090179Benefits and Challenges of <i>Jatropha</i> Meal as Novel Biofeed for Animal ProductionEhsan Oskoueian0Arshin Oskoueian1Majid Shakeri2Mohammad Faseleh Jahromi3Department of Research and Development, Arka Biotechnology Corporation, Mashhad 1696700, IranDepartment of Research and Development, Arka Biotechnology Corporation, Mashhad 1696700, IranDepartment of Medicine, University of Washington, Seattle, WA 98109, USADepartment of Research and Development, Arka Biotechnology Corporation, Mashhad 1696700, Iran<i>Jatropha curcas</i> L. has gained importance as a source of seed oil for biodiesel production. The meal contained about 60% protein with a good balance of essential amino acids, containing various bioactive compounds, including saponins, phytic acids, trypsin inhibitors, lectins, phenolics, and flavonoids, which render it as a potential biofeed for animal production. The <i>Jatropha</i> meal demonstrated various biological activities, including antioxidant, antibacterial, and anti-inflammatory effects which enhance its property as a bio-feed. The levels of these bioactive compounds in the seeds are dependent on the genotypes. The <i>J. curcas</i> possessed different varieties which are either toxic or non-toxic according to the presence of phorbol esters. The presence of phorbol esters in the meal confirmed the toxic variety of <i>Jatropha</i> resulting in the limited application of meal as a biofeed. The <i>Jatropha</i> meal devoid of phorbol esters could be applied as a biofeed in the animal production industry, and for the toxic varieties, various techniques such as physicochemical and biological treatments have been introduced to the industry to remove the phorbol esters from <i>Jatropha</i> meal. Several studies employing various cells and animals confirmed the toxicity of the phorbol esters. The molecular mechanism of action of phorbol esters is through up-regulation of PKC-β II gene, overexpression of down-stream proto-oncogenes resulted in inflammation and oxidative stress ending by apoptotic cell death. Despite the presence of valuable bioactive compounds in the <i>Jatropha</i> meal, its nutritional application is not recommended unless the phorbol esters are completely removed.https://www.mdpi.com/2306-7381/8/9/179<i>Jatropha curcas</i>functional feed additivebioactive compoundsbiological activitynovel protein sourcesanimal production |
| spellingShingle | Ehsan Oskoueian Arshin Oskoueian Majid Shakeri Mohammad Faseleh Jahromi Benefits and Challenges of <i>Jatropha</i> Meal as Novel Biofeed for Animal Production Veterinary Sciences <i>Jatropha curcas</i> functional feed additive bioactive compounds biological activity novel protein sources animal production |
| title | Benefits and Challenges of <i>Jatropha</i> Meal as Novel Biofeed for Animal Production |
| title_full | Benefits and Challenges of <i>Jatropha</i> Meal as Novel Biofeed for Animal Production |
| title_fullStr | Benefits and Challenges of <i>Jatropha</i> Meal as Novel Biofeed for Animal Production |
| title_full_unstemmed | Benefits and Challenges of <i>Jatropha</i> Meal as Novel Biofeed for Animal Production |
| title_short | Benefits and Challenges of <i>Jatropha</i> Meal as Novel Biofeed for Animal Production |
| title_sort | benefits and challenges of i jatropha i meal as novel biofeed for animal production |
| topic | <i>Jatropha curcas</i> functional feed additive bioactive compounds biological activity novel protein sources animal production |
| url | https://www.mdpi.com/2306-7381/8/9/179 |
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