The State of the Immune System in Сhildren with Bronchial Asthma who are at the Stage of Balneological Rehabilitation
Decrease in a-interferon (IFN-a) levels by 6.8% (p > 0.05) compared to the control group, IFN-g by 37.7% (p < 0.05), relative quantity of CD8 + lymphocytes — by 12.26% (p < 0.001) and an increase in the relative amount of CD4 + lymphocytes by 3.9% and CD95 + lymphocytes by 49.73...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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LLC "Diagnostics and Vaccines"
2018-12-01
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| Series: | Детские инфекции (Москва) |
| Subjects: | |
| Online Access: | https://detinf.elpub.ru/jour/article/view/385 |
| _version_ | 1826547067442429952 |
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| author | N. N. Kaladze A. I. Ezernitskaya M. L. Babak |
| author_facet | N. N. Kaladze A. I. Ezernitskaya M. L. Babak |
| author_sort | N. N. Kaladze |
| collection | DOAJ |
| description | Decrease in a-interferon (IFN-a) levels by 6.8% (p > 0.05) compared to the control group, IFN-g by 37.7% (p < 0.05), relative quantity of CD8 + lymphocytes — by 12.26% (p < 0.001) and an increase in the relative amount of CD4 + lymphocytes by 3.9% and CD95 + lymphocytes by 49.73% (p < 0.01), IgE levels 4.1 — fold (p < 0.001) and IL-4 — on 30% it was revealed in 36 children with bronchial asthma, who came to sanatorium-and-spa treatment. An increase in IFN-a levels by 74.7% (p < 0.01) compared with baseline, IFN-g 2.1 — fold (p < 0.001), relative CD8 + lymphocyte count — by 12.26% (p < 0.001) and a significant decrease in the relative amount of CD4 + lymphocytes — by 4.8% (p < 0.05) and CD95 + lymphocytes — by 23.84% (p < 0.01), IgE levels by 28.1% (p < 0.01) and IL-4 — 2.3 times observed after the using a drug containing a2b-interferon and antioxidants vitamins E and C — VIFERON® in the process of balneological treatment. |
| first_indexed | 2024-04-10T03:24:50Z |
| format | Article |
| id | doaj.art-caf1e5d1531549b18a7b0a811e1aaa1b |
| institution | Directory Open Access Journal |
| issn | 2072-8107 |
| language | Russian |
| last_indexed | 2025-03-14T05:43:45Z |
| publishDate | 2018-12-01 |
| publisher | LLC "Diagnostics and Vaccines" |
| record_format | Article |
| series | Детские инфекции (Москва) |
| spelling | doaj.art-caf1e5d1531549b18a7b0a811e1aaa1b2025-03-05T13:50:44ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072018-12-01174121710.22627/2072-8107-2018-17-4-12-17360The State of the Immune System in Сhildren with Bronchial Asthma who are at the Stage of Balneological RehabilitationN. N. Kaladze0A. I. Ezernitskaya1M. L. Babak2Crimean Federal University named after V.I. Vernadsky; Medical Academy named after S.I. GeorgievskyCrimean Federal University named after V.I. Vernadsky; Medical Academy named after S.I. GeorgievskyCrimean Federal University named after V.I. Vernadsky; Medical Academy named after S.I. GeorgievskyDecrease in a-interferon (IFN-a) levels by 6.8% (p > 0.05) compared to the control group, IFN-g by 37.7% (p < 0.05), relative quantity of CD8 + lymphocytes — by 12.26% (p < 0.001) and an increase in the relative amount of CD4 + lymphocytes by 3.9% and CD95 + lymphocytes by 49.73% (p < 0.01), IgE levels 4.1 — fold (p < 0.001) and IL-4 — on 30% it was revealed in 36 children with bronchial asthma, who came to sanatorium-and-spa treatment. An increase in IFN-a levels by 74.7% (p < 0.01) compared with baseline, IFN-g 2.1 — fold (p < 0.001), relative CD8 + lymphocyte count — by 12.26% (p < 0.001) and a significant decrease in the relative amount of CD4 + lymphocytes — by 4.8% (p < 0.05) and CD95 + lymphocytes — by 23.84% (p < 0.01), IgE levels by 28.1% (p < 0.01) and IL-4 — 2.3 times observed after the using a drug containing a2b-interferon and antioxidants vitamins E and C — VIFERON® in the process of balneological treatment.https://detinf.elpub.ru/jour/article/view/385bronchial asthmachildrenimmunity2b-interferonbalneological treatment |
| spellingShingle | N. N. Kaladze A. I. Ezernitskaya M. L. Babak The State of the Immune System in Сhildren with Bronchial Asthma who are at the Stage of Balneological Rehabilitation Детские инфекции (Москва) bronchial asthma children immunity 2b-interferon balneological treatment |
| title | The State of the Immune System in Сhildren with Bronchial Asthma who are at the Stage of Balneological Rehabilitation |
| title_full | The State of the Immune System in Сhildren with Bronchial Asthma who are at the Stage of Balneological Rehabilitation |
| title_fullStr | The State of the Immune System in Сhildren with Bronchial Asthma who are at the Stage of Balneological Rehabilitation |
| title_full_unstemmed | The State of the Immune System in Сhildren with Bronchial Asthma who are at the Stage of Balneological Rehabilitation |
| title_short | The State of the Immune System in Сhildren with Bronchial Asthma who are at the Stage of Balneological Rehabilitation |
| title_sort | state of the immune system in сhildren with bronchial asthma who are at the stage of balneological rehabilitation |
| topic | bronchial asthma children immunity 2b-interferon balneological treatment |
| url | https://detinf.elpub.ru/jour/article/view/385 |
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