A Perspective on Osteoarthritis Research in Singapore
Knee osteoarthritis (OA) is common and is one of the five leading causes of disability in Singapore; it entails significant cost to society. Singapore is one of the faster ageing populations in Asia and obesity is on the rise. The public health consequences of OA, particularly knee OA are therefore...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2013-03-01
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| Series: | Proceedings of Singapore Healthcare |
| Online Access: | https://doi.org/10.1177/201010581302200106 |
| _version_ | 1831715219535036416 |
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| author | Ying Ying Leung MBChB, FHKAM (MED) Yong Hao Pua BSc, PhD Julian Thumboo FRCP (Edin), FAMS (Rheumatology) |
| author_facet | Ying Ying Leung MBChB, FHKAM (MED) Yong Hao Pua BSc, PhD Julian Thumboo FRCP (Edin), FAMS (Rheumatology) |
| author_sort | Ying Ying Leung MBChB, FHKAM (MED) |
| collection | DOAJ |
| description | Knee osteoarthritis (OA) is common and is one of the five leading causes of disability in Singapore; it entails significant cost to society. Singapore is one of the faster ageing populations in Asia and obesity is on the rise. The public health consequences of OA, particularly knee OA are therefore expected to rise dramatically. There is thus an urgent need for advancement in research in this area. An accurate estimate of the prevalence of knee OA would improve the understanding of its impact in different sectors of society, and facilitate public health decision-making and resource allocation to address this upcoming challenge in public health. Currently there is no proven drug that slows down the osteoarthritis process and management of knee OA is symptomatic. Identification of genetic, environmental, inflammatory and biomechanical risk factors will help us to understand the pathogenesis and find factors for its prevention. There is a need for early diagnosis of knee OA and identifying subjects who are more likely to benefit from drug treatment. Effort is needed in the discovery of drugs that have disease modifying effect to treat this disabling disease. Understanding the biomechanical factors underlying knee OA may also lead to the discovery of new recommendation and treatment strategies. |
| first_indexed | 2024-12-21T00:14:56Z |
| format | Article |
| id | doaj.art-caf3097e9fe84cbb8b7ca036c705c566 |
| institution | Directory Open Access Journal |
| issn | 2010-1058 2059-2329 |
| language | English |
| last_indexed | 2024-12-21T00:14:56Z |
| publishDate | 2013-03-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Proceedings of Singapore Healthcare |
| spelling | doaj.art-caf3097e9fe84cbb8b7ca036c705c5662022-12-21T19:22:15ZengSAGE PublishingProceedings of Singapore Healthcare2010-10582059-23292013-03-012210.1177/201010581302200106A Perspective on Osteoarthritis Research in SingaporeYing Ying Leung MBChB, FHKAM (MED)0Yong Hao Pua BSc, PhD1Julian Thumboo FRCP (Edin), FAMS (Rheumatology)2 Department of Rheumatology and Immunology, Singapore General Hospital Department of Physiotherapy, Singapore General Hospital Department of Rheumatology and Immunology, Singapore General HospitalKnee osteoarthritis (OA) is common and is one of the five leading causes of disability in Singapore; it entails significant cost to society. Singapore is one of the faster ageing populations in Asia and obesity is on the rise. The public health consequences of OA, particularly knee OA are therefore expected to rise dramatically. There is thus an urgent need for advancement in research in this area. An accurate estimate of the prevalence of knee OA would improve the understanding of its impact in different sectors of society, and facilitate public health decision-making and resource allocation to address this upcoming challenge in public health. Currently there is no proven drug that slows down the osteoarthritis process and management of knee OA is symptomatic. Identification of genetic, environmental, inflammatory and biomechanical risk factors will help us to understand the pathogenesis and find factors for its prevention. There is a need for early diagnosis of knee OA and identifying subjects who are more likely to benefit from drug treatment. Effort is needed in the discovery of drugs that have disease modifying effect to treat this disabling disease. Understanding the biomechanical factors underlying knee OA may also lead to the discovery of new recommendation and treatment strategies.https://doi.org/10.1177/201010581302200106 |
| spellingShingle | Ying Ying Leung MBChB, FHKAM (MED) Yong Hao Pua BSc, PhD Julian Thumboo FRCP (Edin), FAMS (Rheumatology) A Perspective on Osteoarthritis Research in Singapore Proceedings of Singapore Healthcare |
| title | A Perspective on Osteoarthritis Research in Singapore |
| title_full | A Perspective on Osteoarthritis Research in Singapore |
| title_fullStr | A Perspective on Osteoarthritis Research in Singapore |
| title_full_unstemmed | A Perspective on Osteoarthritis Research in Singapore |
| title_short | A Perspective on Osteoarthritis Research in Singapore |
| title_sort | perspective on osteoarthritis research in singapore |
| url | https://doi.org/10.1177/201010581302200106 |
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