Multi-Omic Analysis in a Metabolic Syndrome Porcine Model Implicates Arachidonic Acid Metabolism Disorder as a Risk Factor for Atherosclerosis

Multi-Omic Analysis in a Metabolic Syndrome Porcine Model Implicates Arachidonic Acid Metabolism Disorder as a Risk Factor for Atherosclerosis

BackgroundThe diet-induced gut microbiota dysbiosis has been suggested as a major risk factor for atherothrombosis, however, the detailed mechanism linking these conditions is yet to be fully understood.MethodsWe established a long-term excessive-energy diet-induced metabolic syndrome (MetS) inbred...

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Bibliographic Details
Main Authors: Song-Song Xu, Xiu-Ling Zhang, Sha-Sha Liu, Shu-Tang Feng, Guang-Ming Xiang, Chang-Jiang Xu, Zi-Yao Fan, Kui Xu, Nan Wang, Yue Wang, Jing-Jing Che, Zhi-Guo Liu, Yu-Lian Mu, Kui Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Nutrition
Subjects:
atherothrombosis
metagenome
metatranscriptome
metabolome
transcriptome
inflammatory response
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.807118/full

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