Pancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involved
Editorial summary Recent advances in β-cell regeneration in vivo are providing insights into the mechanisms involved in the conversion of distinct pancreatic cell lineages into β cells. These mechanisms mostly involve reactivation of the gene encoding the pancreatic endocrine cell-specifying transcr...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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BMC
2017-05-01
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| Series: | Genome Medicine |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13073-017-0437-x |
| _version_ | 1828353966779400192 |
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| author | Solomon Afelik Meritxell Rovira |
| author_facet | Solomon Afelik Meritxell Rovira |
| author_sort | Solomon Afelik |
| collection | DOAJ |
| description | Editorial summary Recent advances in β-cell regeneration in vivo are providing insights into the mechanisms involved in the conversion of distinct pancreatic cell lineages into β cells. These mechanisms mostly involve reactivation of the gene encoding the pancreatic endocrine cell-specifying transcription factor neurogenin-3. |
| first_indexed | 2024-04-14T02:16:58Z |
| format | Article |
| id | doaj.art-caf83d462bee49b1863656db157d452e |
| institution | Directory Open Access Journal |
| issn | 1756-994X |
| language | English |
| last_indexed | 2024-04-14T02:16:58Z |
| publishDate | 2017-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Genome Medicine |
| spelling | doaj.art-caf83d462bee49b1863656db157d452e2022-12-22T02:18:11ZengBMCGenome Medicine1756-994X2017-05-01911410.1186/s13073-017-0437-xPancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involvedSolomon Afelik0Meritxell Rovira1Division of Transplantation, Department of Surgery, University of Illinois at ChicagoCenter of Regenerative Medicine in Barcelona (CMRB)Editorial summary Recent advances in β-cell regeneration in vivo are providing insights into the mechanisms involved in the conversion of distinct pancreatic cell lineages into β cells. These mechanisms mostly involve reactivation of the gene encoding the pancreatic endocrine cell-specifying transcription factor neurogenin-3.http://link.springer.com/article/10.1186/s13073-017-0437-xAcinar CellDuctal CellPancreatic Acinar CellArtemetherCell Conversion |
| spellingShingle | Solomon Afelik Meritxell Rovira Pancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involved Genome Medicine Acinar Cell Ductal Cell Pancreatic Acinar Cell Artemether Cell Conversion |
| title | Pancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involved |
| title_full | Pancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involved |
| title_fullStr | Pancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involved |
| title_full_unstemmed | Pancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involved |
| title_short | Pancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involved |
| title_sort | pancreatic β cell regeneration advances in understanding the genes and signaling pathways involved |
| topic | Acinar Cell Ductal Cell Pancreatic Acinar Cell Artemether Cell Conversion |
| url | http://link.springer.com/article/10.1186/s13073-017-0437-x |
| work_keys_str_mv | AT solomonafelik pancreaticbcellregenerationadvancesinunderstandingthegenesandsignalingpathwaysinvolved AT meritxellrovira pancreaticbcellregenerationadvancesinunderstandingthegenesandsignalingpathwaysinvolved |