Cerebral palsy and developmental intellectual disability in children younger than 5 years: Findings from the GBD-WHO Rehabilitation Database 2019
ObjectiveChildren with developmental disabilities are associated with a high risk of poor school enrollment and educational attainment without timely and appropriate support. Epidemiological data on cerebral palsy and associated comorbidities required for policy intervention in global health are lac...
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2022.894546/full |
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| author | Bolajoko O. Olusanya Melissa Gladstone Scott M. Wright Mijna Hadders-Algra Nem-Yun Boo M. K. C. Nair Nihad Almasri Vijaya Kancherla Maureen E. Samms-Vaughan Angelina Kakooza-Mwesige Tracey Smythe Christie del Castillo-Hegyi Ricardo Halpern Olaf K. de Camargo Jalal Arabloo Aziz Eftekhari Amira Shaheen Sheffali Gulati Andrew N. Williams Jacob O. Olusanya Donald Wertlieb Charles R. J. Newton Adrian C. Davis Adrian C. Davis |
| author_facet | Bolajoko O. Olusanya Melissa Gladstone Scott M. Wright Mijna Hadders-Algra Nem-Yun Boo M. K. C. Nair Nihad Almasri Vijaya Kancherla Maureen E. Samms-Vaughan Angelina Kakooza-Mwesige Tracey Smythe Christie del Castillo-Hegyi Ricardo Halpern Olaf K. de Camargo Jalal Arabloo Aziz Eftekhari Amira Shaheen Sheffali Gulati Andrew N. Williams Jacob O. Olusanya Donald Wertlieb Charles R. J. Newton Adrian C. Davis Adrian C. Davis |
| author_sort | Bolajoko O. Olusanya |
| collection | DOAJ |
| description | ObjectiveChildren with developmental disabilities are associated with a high risk of poor school enrollment and educational attainment without timely and appropriate support. Epidemiological data on cerebral palsy and associated comorbidities required for policy intervention in global health are lacking. This paper set out to report the best available evidence on the global and regional prevalence of cerebral palsy (CP) and developmental intellectual disability and the associated “years lived with disability” (YLDs) among children under 5 years of age in 2019.MethodsWe analyzed the collaborative 2019 Rehabilitation Database of the Global Burden of Disease (GBD) Study and World Health Organization for neurological and mental disorders available for 204 countries and territories. Point prevalence and YLDs with 95% uncertainty intervals (UI) are presented.ResultsGlobally, 8.1 million (7.1–9.2) or 1.2% of children under 5 years are estimated to have CP with 16.1 million (11.5–21.0) or 2.4% having intellectual disability. Over 98% resided in low-income and middle-income countries (LMICs). CP and intellectual disability accounted for 6.5% and 4.5% of the aggregate YLDs from all causes of adverse health outcomes respectively. African Region recorded the highest prevalence of CP (1.6%) while South-East Asia Region had the highest prevalence of intellectual disability. The top 10 countries accounted for 57.2% of the global prevalence of CP and 62.0% of the global prevalence of intellectual disability.ConclusionBased on this Database, CP and intellectual disability are highly prevalent and associated with substantial YLDs among children under 5 years worldwide. Universal early detection and support services are warranted, particularly in LMICs to optimize school readiness for these children toward inclusive education as envisioned by the United Nations' Sustainable Development Goals. |
| first_indexed | 2024-04-11T21:15:13Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-04-11T21:15:13Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Public Health |
| spelling | doaj.art-cb010a59247040e491683921350a1af72022-12-22T04:02:50ZengFrontiers Media S.A.Frontiers in Public Health2296-25652022-08-011010.3389/fpubh.2022.894546894546Cerebral palsy and developmental intellectual disability in children younger than 5 years: Findings from the GBD-WHO Rehabilitation Database 2019Bolajoko O. Olusanya0Melissa Gladstone1Scott M. Wright2Mijna Hadders-Algra3Nem-Yun Boo4M. K. C. Nair5Nihad Almasri6Vijaya Kancherla7Maureen E. Samms-Vaughan8Angelina Kakooza-Mwesige9Tracey Smythe10Christie del Castillo-Hegyi11Ricardo Halpern12Olaf K. de Camargo13Jalal Arabloo14Aziz Eftekhari15Amira Shaheen16Sheffali Gulati17Andrew N. Williams18Jacob O. Olusanya19Donald Wertlieb20Charles R. J. Newton21Adrian C. Davis22Adrian C. Davis23Centre for Healthy Start Initiative, Lagos, NigeriaDepartment of Women and Children's Health, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, United KingdomDivision of General Internal Medicine, Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, MD, United StatesDivision of Developmental Neurology, Department of Paediatrics, University Medical Center Groningen, University of Groningen, Groningen, NetherlandsDepartment of Population Medicine, Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Selangor, MalaysiaChild Development Centre, Thiruvananthapuram Medical College, Thiruvananthapuram, Kerala, IndiaDepartment of Physiotherapy, The University of Jordan, Amman, JordanDepartment of Epidemiology Epidemiologist, Center for Spina Bifida Prevention Rollins School of Public Health, Emory University, Atlanta, GA, United StatesDepartment of Child and Adolescent Health, The University of the West Indies, Kingston, Jamaica0Department of Pediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda1International Centre for Evidence in Disability, London School of Hygiene & Tropical Medicine, London, United Kingdom2Department of Emergency Medicine, CHI St. Vincent, Little Rock, AR, United States3Child Development Outpatient Clinic, Hospital da Criança Santo Antônio, Santa Casa de Porto Alegre, Porto Alegre, RS, Brazil4CanChild Centre for Childhood Disability Research, McMaster University, Hamilton, ON, Canada5Health Management and Economics Research Center, Health Management Research Institute, Iran University of Medical Sciences, Tehran, Iran6Department of Toxicology and Pharmacology, Tabriz University of Medical Sciences, Tabriz, Iran7Division of Public Health, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine8Center of Excellence & Advanced Research on Childhood Neurodevelopmental Disorders, Child Neurology Division, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India9Virtual Academic Unit, Children's Directorate, Northampton General Hospital, Northampton, United KingdomCentre for Healthy Start Initiative, Lagos, Nigeria0Eliot-Pearson Department of Child Development, Tufts University, Medford, MA, United States1Kenya Medical Research Institute–Wellcome Trust Research Programme, Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute, KiIifi, Kenya2Department of Population Health Sciences, London School of Economics, London, United Kingdom3Vision and Eye Research Institute, School of Medicine, Anglia Ruskin University, Cambridge, United KingdomObjectiveChildren with developmental disabilities are associated with a high risk of poor school enrollment and educational attainment without timely and appropriate support. Epidemiological data on cerebral palsy and associated comorbidities required for policy intervention in global health are lacking. This paper set out to report the best available evidence on the global and regional prevalence of cerebral palsy (CP) and developmental intellectual disability and the associated “years lived with disability” (YLDs) among children under 5 years of age in 2019.MethodsWe analyzed the collaborative 2019 Rehabilitation Database of the Global Burden of Disease (GBD) Study and World Health Organization for neurological and mental disorders available for 204 countries and territories. Point prevalence and YLDs with 95% uncertainty intervals (UI) are presented.ResultsGlobally, 8.1 million (7.1–9.2) or 1.2% of children under 5 years are estimated to have CP with 16.1 million (11.5–21.0) or 2.4% having intellectual disability. Over 98% resided in low-income and middle-income countries (LMICs). CP and intellectual disability accounted for 6.5% and 4.5% of the aggregate YLDs from all causes of adverse health outcomes respectively. African Region recorded the highest prevalence of CP (1.6%) while South-East Asia Region had the highest prevalence of intellectual disability. The top 10 countries accounted for 57.2% of the global prevalence of CP and 62.0% of the global prevalence of intellectual disability.ConclusionBased on this Database, CP and intellectual disability are highly prevalent and associated with substantial YLDs among children under 5 years worldwide. Universal early detection and support services are warranted, particularly in LMICs to optimize school readiness for these children toward inclusive education as envisioned by the United Nations' Sustainable Development Goals.https://www.frontiersin.org/articles/10.3389/fpubh.2022.894546/fullcerebral palsyintellectual disabilityrehabilitationglobal healthdevelopmental disabilitiesglobal burden of disease |
| spellingShingle | Bolajoko O. Olusanya Melissa Gladstone Scott M. Wright Mijna Hadders-Algra Nem-Yun Boo M. K. C. Nair Nihad Almasri Vijaya Kancherla Maureen E. Samms-Vaughan Angelina Kakooza-Mwesige Tracey Smythe Christie del Castillo-Hegyi Ricardo Halpern Olaf K. de Camargo Jalal Arabloo Aziz Eftekhari Amira Shaheen Sheffali Gulati Andrew N. Williams Jacob O. Olusanya Donald Wertlieb Charles R. J. Newton Adrian C. Davis Adrian C. Davis Cerebral palsy and developmental intellectual disability in children younger than 5 years: Findings from the GBD-WHO Rehabilitation Database 2019 Frontiers in Public Health cerebral palsy intellectual disability rehabilitation global health developmental disabilities global burden of disease |
| title | Cerebral palsy and developmental intellectual disability in children younger than 5 years: Findings from the GBD-WHO Rehabilitation Database 2019 |
| title_full | Cerebral palsy and developmental intellectual disability in children younger than 5 years: Findings from the GBD-WHO Rehabilitation Database 2019 |
| title_fullStr | Cerebral palsy and developmental intellectual disability in children younger than 5 years: Findings from the GBD-WHO Rehabilitation Database 2019 |
| title_full_unstemmed | Cerebral palsy and developmental intellectual disability in children younger than 5 years: Findings from the GBD-WHO Rehabilitation Database 2019 |
| title_short | Cerebral palsy and developmental intellectual disability in children younger than 5 years: Findings from the GBD-WHO Rehabilitation Database 2019 |
| title_sort | cerebral palsy and developmental intellectual disability in children younger than 5 years findings from the gbd who rehabilitation database 2019 |
| topic | cerebral palsy intellectual disability rehabilitation global health developmental disabilities global burden of disease |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2022.894546/full |
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