A new soft tissue constructed with chitosan for wound dressings-incorporating nanoparticles for medical and nursing therapeutic efficacy

The skin, being the largest organ in the human body, plays a vital role in shielding internal organs from external physical and chemical factors. However, skin damage caused by various factors such as injuries, surgeries, diabetes, or burns can lead to wounds that diminish the skin's protective...

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Main Authors: Minhui Yang, Haibing Wang, Kang Li, Zhongyu Chen, D.T. Seamirumi
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Regenerative Therapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320423000536
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author Minhui Yang
Haibing Wang
Kang Li
Zhongyu Chen
D.T. Seamirumi
author_facet Minhui Yang
Haibing Wang
Kang Li
Zhongyu Chen
D.T. Seamirumi
author_sort Minhui Yang
collection DOAJ
description The skin, being the largest organ in the human body, plays a vital role in shielding internal organs from external physical and chemical factors. However, skin damage caused by various factors such as injuries, surgeries, diabetes, or burns can lead to wounds that diminish the skin's protective function. Monitoring essential physiological parameters like temperature, moisture, and pH is crucial to facilitate antibiotic treatment, remote physician monitoring, patient comfort, cost reduction, and prevention of hospital-acquired infections. To this end, innovative wound coverings made of biological materials like gelatin, carboxymethyl chitosan, and titanium nanoparticles have been developed, mainly for hospital and pediatric applications. These wound coverings come equipped with sensors to monitor temperature, pH, and moisture and are suitable for pediatric hospitals where children experience difficulty in wound healing due to their sensitive skin. The temperature monitoring feature allows physicians to accurately assess the wound's temperature, detect potential infections, and take prompt actions. These wound coverings can significantly enhance wound treatment for patients, as real-time monitoring of physiological parameters enables informed decision-making by physicians, leading to better therapeutic outcomes. Furthermore, the use of these wound coverings can minimize the risk of hospital-acquired infections. Their adaptability and flexibility make them ideal for various wound types and sizes, ensuring patient comfort and compliance with the treatment plan. In conclusion, the development of innovative and flexible wound coverings using biological materials and equipped with sensors represents a significant breakthrough in wound management. The use of these wound coverings has the potential to revolutionize wound care and improve patient outcomes, particularly in pediatric hospitals where wound healing is often challenging.
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spelling doaj.art-cb09f2c4e29348768d7594692503f4b02023-11-30T05:07:44ZengElsevierRegenerative Therapy2352-32042023-12-0124103111A new soft tissue constructed with chitosan for wound dressings-incorporating nanoparticles for medical and nursing therapeutic efficacyMinhui Yang0Haibing Wang1Kang Li2Zhongyu Chen3D.T. Seamirumi4Department of Orthopedics, Fuzhou First Hospital of Fujian Medical University, No.190, Dadao Road, Taijiang District, Fuzhou, Fujian, 350000, ChinaDepartment of Orthopedics, Fuzhou First Hospital of Fujian Medical University, No.190, Dadao Road, Taijiang District, Fuzhou, Fujian, 350000, ChinaDepartment of Pediatric Surgery, Fuzhou Children's Hospital of Fujian Medical University, No.145, No.817 Middle Road, Gulou District, Fuzhou, Fujian, 350004, ChinaDepartment of Orthopedics,The Fifth Hospital of Xiamen, No. 101, Min ‘an Road, Ma Xiang Street, Xiang ‘an District, Xiamen, Fujian, 361101, China; Corresponding author.Faculty of Biomaterials, Advanced Materials Research Center, Isfahan, IranThe skin, being the largest organ in the human body, plays a vital role in shielding internal organs from external physical and chemical factors. However, skin damage caused by various factors such as injuries, surgeries, diabetes, or burns can lead to wounds that diminish the skin's protective function. Monitoring essential physiological parameters like temperature, moisture, and pH is crucial to facilitate antibiotic treatment, remote physician monitoring, patient comfort, cost reduction, and prevention of hospital-acquired infections. To this end, innovative wound coverings made of biological materials like gelatin, carboxymethyl chitosan, and titanium nanoparticles have been developed, mainly for hospital and pediatric applications. These wound coverings come equipped with sensors to monitor temperature, pH, and moisture and are suitable for pediatric hospitals where children experience difficulty in wound healing due to their sensitive skin. The temperature monitoring feature allows physicians to accurately assess the wound's temperature, detect potential infections, and take prompt actions. These wound coverings can significantly enhance wound treatment for patients, as real-time monitoring of physiological parameters enables informed decision-making by physicians, leading to better therapeutic outcomes. Furthermore, the use of these wound coverings can minimize the risk of hospital-acquired infections. Their adaptability and flexibility make them ideal for various wound types and sizes, ensuring patient comfort and compliance with the treatment plan. In conclusion, the development of innovative and flexible wound coverings using biological materials and equipped with sensors represents a significant breakthrough in wound management. The use of these wound coverings has the potential to revolutionize wound care and improve patient outcomes, particularly in pediatric hospitals where wound healing is often challenging.http://www.sciencedirect.com/science/article/pii/S2352320423000536Pediatric hospitalsHospital-acquired infectionsVital physiological parametersInnovative wound coverings
spellingShingle Minhui Yang
Haibing Wang
Kang Li
Zhongyu Chen
D.T. Seamirumi
A new soft tissue constructed with chitosan for wound dressings-incorporating nanoparticles for medical and nursing therapeutic efficacy
Regenerative Therapy
Pediatric hospitals
Hospital-acquired infections
Vital physiological parameters
Innovative wound coverings
title A new soft tissue constructed with chitosan for wound dressings-incorporating nanoparticles for medical and nursing therapeutic efficacy
title_full A new soft tissue constructed with chitosan for wound dressings-incorporating nanoparticles for medical and nursing therapeutic efficacy
title_fullStr A new soft tissue constructed with chitosan for wound dressings-incorporating nanoparticles for medical and nursing therapeutic efficacy
title_full_unstemmed A new soft tissue constructed with chitosan for wound dressings-incorporating nanoparticles for medical and nursing therapeutic efficacy
title_short A new soft tissue constructed with chitosan for wound dressings-incorporating nanoparticles for medical and nursing therapeutic efficacy
title_sort new soft tissue constructed with chitosan for wound dressings incorporating nanoparticles for medical and nursing therapeutic efficacy
topic Pediatric hospitals
Hospital-acquired infections
Vital physiological parameters
Innovative wound coverings
url http://www.sciencedirect.com/science/article/pii/S2352320423000536
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