The Role of the Pentose Phosphate Pathway in Diabetes and Cancer

The pentose phosphate pathway (PPP) branches from glucose 6-phosphate (G6P), produces NADPH and ribose 5-phosphate (R5P), and shunts carbons back to the glycolytic or gluconeogenic pathway. The PPP has been demonstrated to be a major regulator for cellular reduction-oxidation (redox) homeostasis and...

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Hlavní autoři: Tongxin Ge, Jiawen Yang, Shihui Zhou, Yuchen Wang, Yakui Li, Xuemei Tong
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2020-06-01
Edice:Frontiers in Endocrinology
Témata:
On-line přístup:https://www.frontiersin.org/article/10.3389/fendo.2020.00365/full