Trends in utilization of lipid- and blood pressure-lowering agents and goal attainment among the U.S. diabetic population, 1999-2008
<p>Abstract</p> <p>Background</p> <p>For patients with diabetes, clinical practice guidelines recommend treating to a low-density lipoprotein cholesterol (LDL-C) goal of <2.59 mmol/L (100 mg/dL) and a blood pressure (BP) target of <130/80 mmHg. This analysis asses...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-04-01
|
| Series: | Cardiovascular Diabetology |
| Online Access: | http://www.cardiab.com/content/10/1/31 |
| _version_ | 1811286894265237504 |
|---|---|
| author | Kuznik Andreas Mardekian Jack |
| author_facet | Kuznik Andreas Mardekian Jack |
| author_sort | Kuznik Andreas |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>For patients with diabetes, clinical practice guidelines recommend treating to a low-density lipoprotein cholesterol (LDL-C) goal of <2.59 mmol/L (100 mg/dL) and a blood pressure (BP) target of <130/80 mmHg. This analysis assessed recent trends in the utilization of lipid-lowering and BP-lowering agents, as well as LDL-C and BP goal attainment, in the U.S. adult diabetic population.</p> <p>Methods</p> <p>9,167 men and nonpregnant women aged ≥20 years were identified from the fasting subsample of the 1999-2008 National Health and Nutritional Examination Survey. Diabetes was identified in 1,214 participants by self report, self-reported use of insulin or oral medications for diabetes, or fasting glucose ≥6.99 mmol/L (126 mg/dL).</p> <p>Results</p> <p>The prevalence of diagnosed or undiagnosed diabetes increased significantly over the past decade, from 7.4% in 1999-2000 to 11.9% in 2007-2008 (<it>P </it>= 0.0007). During this period, the use of lipid-lowering agents by participants with diabetes increased from 19.5% to 42.2% (<it>P </it>< 0.0001), and the proportion at LDL-C goal increased from 29.7% to 54.4% (<it>P </it>< 0.0001). Although there was a significant increase in antihypertensive medication use (from 35.4% to 58.9%; <it>P </it>< 0.0001), there was no significant change in the proportion of participants at BP goal (from 47.6% to 55.1%; <it>P </it>= 0.1333) or prevalence of hypertension (from 66.6% to 74.2%; <it>P </it>= 0.3724).</p> <p>Conclusions</p> <p>The proportion of diabetic individuals taking lipid- and BP-lowering agents has increased significantly in recent years. However, while there has been a significant improvement in LDL-C goal attainment, nearly one-half of all U.S. adults with diabetes are not at recommended LDL-C or BP treatment goals.</p> |
| first_indexed | 2024-04-13T03:09:06Z |
| format | Article |
| id | doaj.art-cb0c3c28c36c46f8b67ca6a1e61d16e8 |
| institution | Directory Open Access Journal |
| issn | 1475-2840 |
| language | English |
| last_indexed | 2024-04-13T03:09:06Z |
| publishDate | 2011-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Cardiovascular Diabetology |
| spelling | doaj.art-cb0c3c28c36c46f8b67ca6a1e61d16e82022-12-22T03:05:09ZengBMCCardiovascular Diabetology1475-28402011-04-011013110.1186/1475-2840-10-31Trends in utilization of lipid- and blood pressure-lowering agents and goal attainment among the U.S. diabetic population, 1999-2008Kuznik AndreasMardekian Jack<p>Abstract</p> <p>Background</p> <p>For patients with diabetes, clinical practice guidelines recommend treating to a low-density lipoprotein cholesterol (LDL-C) goal of <2.59 mmol/L (100 mg/dL) and a blood pressure (BP) target of <130/80 mmHg. This analysis assessed recent trends in the utilization of lipid-lowering and BP-lowering agents, as well as LDL-C and BP goal attainment, in the U.S. adult diabetic population.</p> <p>Methods</p> <p>9,167 men and nonpregnant women aged ≥20 years were identified from the fasting subsample of the 1999-2008 National Health and Nutritional Examination Survey. Diabetes was identified in 1,214 participants by self report, self-reported use of insulin or oral medications for diabetes, or fasting glucose ≥6.99 mmol/L (126 mg/dL).</p> <p>Results</p> <p>The prevalence of diagnosed or undiagnosed diabetes increased significantly over the past decade, from 7.4% in 1999-2000 to 11.9% in 2007-2008 (<it>P </it>= 0.0007). During this period, the use of lipid-lowering agents by participants with diabetes increased from 19.5% to 42.2% (<it>P </it>< 0.0001), and the proportion at LDL-C goal increased from 29.7% to 54.4% (<it>P </it>< 0.0001). Although there was a significant increase in antihypertensive medication use (from 35.4% to 58.9%; <it>P </it>< 0.0001), there was no significant change in the proportion of participants at BP goal (from 47.6% to 55.1%; <it>P </it>= 0.1333) or prevalence of hypertension (from 66.6% to 74.2%; <it>P </it>= 0.3724).</p> <p>Conclusions</p> <p>The proportion of diabetic individuals taking lipid- and BP-lowering agents has increased significantly in recent years. However, while there has been a significant improvement in LDL-C goal attainment, nearly one-half of all U.S. adults with diabetes are not at recommended LDL-C or BP treatment goals.</p>http://www.cardiab.com/content/10/1/31 |
| spellingShingle | Kuznik Andreas Mardekian Jack Trends in utilization of lipid- and blood pressure-lowering agents and goal attainment among the U.S. diabetic population, 1999-2008 Cardiovascular Diabetology |
| title | Trends in utilization of lipid- and blood pressure-lowering agents and goal attainment among the U.S. diabetic population, 1999-2008 |
| title_full | Trends in utilization of lipid- and blood pressure-lowering agents and goal attainment among the U.S. diabetic population, 1999-2008 |
| title_fullStr | Trends in utilization of lipid- and blood pressure-lowering agents and goal attainment among the U.S. diabetic population, 1999-2008 |
| title_full_unstemmed | Trends in utilization of lipid- and blood pressure-lowering agents and goal attainment among the U.S. diabetic population, 1999-2008 |
| title_short | Trends in utilization of lipid- and blood pressure-lowering agents and goal attainment among the U.S. diabetic population, 1999-2008 |
| title_sort | trends in utilization of lipid and blood pressure lowering agents and goal attainment among the u s diabetic population 1999 2008 |
| url | http://www.cardiab.com/content/10/1/31 |
| work_keys_str_mv | AT kuznikandreas trendsinutilizationoflipidandbloodpressureloweringagentsandgoalattainmentamongtheusdiabeticpopulation19992008 AT mardekianjack trendsinutilizationoflipidandbloodpressureloweringagentsandgoalattainmentamongtheusdiabeticpopulation19992008 |