Functional Expression of Multidrug-Resistance (MDR) Transporters in Developing Human Fetal Brain Endothelial Cells

Functional Expression of Multidrug-Resistance (MDR) Transporters in Developing Human Fetal Brain Endothelial Cells

There is little information about the functional expression of the multidrug resistance (MDR) transporters P-glycoprotein (P-gp, encoded by <i>ABCB1</i>) and breast cancer resistance protein (BCRP/<i>ABCG2</i>) in the developing blood–brain barrier (BBB). We isolated and cult...

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Bibliographic Details
Main Authors:	Phetcharawan Lye, Enrrico Bloise, Guinever E. Imperio, David Chitayat, Stephen G. Matthews
Format:	Article
Language:	English
Published:	MDPI AG 2022-07-01
Series:	Cells
Subjects:	developing human blood–brain barrier (BBB) P-glycoprotein (P-gp/<i>ABCB1</i>) breast cancer resistance protein (BCRP/<i>ABCG2</i>) fetal brain endothelial cells (BECs) tube formation
Online Access:	https://www.mdpi.com/2073-4409/11/14/2259

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