Identification of Knowledge Gaps Regarding Healthcare Workers' Exposure to Antineoplastic Drugs: Review of Literature, North America versus Europe

We have been examining the issue of healthcare workers' exposure to antineoplastic drugs for nearly a decade and have observed that there appears to be more publications on the subject matter originating from Europe than from North America. The concern is that findings from Europe may not be ge...

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Main Authors: Chun-Yip Hon, Cris Barzan, George Astrakianakis
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Safety and Health at Work
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2093791114000432
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author Chun-Yip Hon
Cris Barzan
George Astrakianakis
author_facet Chun-Yip Hon
Cris Barzan
George Astrakianakis
author_sort Chun-Yip Hon
collection DOAJ
description We have been examining the issue of healthcare workers' exposure to antineoplastic drugs for nearly a decade and have observed that there appears to be more publications on the subject matter originating from Europe than from North America. The concern is that findings from Europe may not be generalizable to North America because of differences in handling practices, regulatory requirements, and training. Our objective was to perform a literature review to confirm our observation and, in turn, identify gaps in knowledge that warrants addressing in North America. Using select keywords, we searched for publications in PubMed and Web of Science. All papers were initially classified according to the originating continent and then categorized into one or more subject categories (analytical methods, biological monitoring, occupational exposure, surface contamination, and probability of risk/exposure). Our review identified 16 papers originating from North America and 55 papers from Europe with surface contamination being the subject matter most often studied overall. Based on our results, we are of the opinion that North American researchers need to further conduct dermal and/or urinary drug contamination studies as well as assess the exposure risk faced by healthcare workers who handle antineoplastic drugs. Trends in exposure levels should also be explored.
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spelling doaj.art-cb0f2c09004c40689f476f4680a6b0d72023-09-02T18:14:07ZengElsevierSafety and Health at Work2093-79112014-12-015416917410.1016/j.shaw.2014.06.001Identification of Knowledge Gaps Regarding Healthcare Workers' Exposure to Antineoplastic Drugs: Review of Literature, North America versus EuropeChun-Yip Hon0Cris Barzan1George Astrakianakis2School of Occupational and Public Health, Ryerson University, Toronto, Ontario, CanadaSchool of Population and Public Health, University of British Columbia, Vancouver, British Columbia, CanadaSchool of Population and Public Health, University of British Columbia, Vancouver, British Columbia, CanadaWe have been examining the issue of healthcare workers' exposure to antineoplastic drugs for nearly a decade and have observed that there appears to be more publications on the subject matter originating from Europe than from North America. The concern is that findings from Europe may not be generalizable to North America because of differences in handling practices, regulatory requirements, and training. Our objective was to perform a literature review to confirm our observation and, in turn, identify gaps in knowledge that warrants addressing in North America. Using select keywords, we searched for publications in PubMed and Web of Science. All papers were initially classified according to the originating continent and then categorized into one or more subject categories (analytical methods, biological monitoring, occupational exposure, surface contamination, and probability of risk/exposure). Our review identified 16 papers originating from North America and 55 papers from Europe with surface contamination being the subject matter most often studied overall. Based on our results, we are of the opinion that North American researchers need to further conduct dermal and/or urinary drug contamination studies as well as assess the exposure risk faced by healthcare workers who handle antineoplastic drugs. Trends in exposure levels should also be explored.http://www.sciencedirect.com/science/article/pii/S2093791114000432antineoplastic drugshealthcare workersknowledge gapsoccupational exposure
spellingShingle Chun-Yip Hon
Cris Barzan
George Astrakianakis
Identification of Knowledge Gaps Regarding Healthcare Workers' Exposure to Antineoplastic Drugs: Review of Literature, North America versus Europe
Safety and Health at Work
antineoplastic drugs
healthcare workers
knowledge gaps
occupational exposure
title Identification of Knowledge Gaps Regarding Healthcare Workers' Exposure to Antineoplastic Drugs: Review of Literature, North America versus Europe
title_full Identification of Knowledge Gaps Regarding Healthcare Workers' Exposure to Antineoplastic Drugs: Review of Literature, North America versus Europe
title_fullStr Identification of Knowledge Gaps Regarding Healthcare Workers' Exposure to Antineoplastic Drugs: Review of Literature, North America versus Europe
title_full_unstemmed Identification of Knowledge Gaps Regarding Healthcare Workers' Exposure to Antineoplastic Drugs: Review of Literature, North America versus Europe
title_short Identification of Knowledge Gaps Regarding Healthcare Workers' Exposure to Antineoplastic Drugs: Review of Literature, North America versus Europe
title_sort identification of knowledge gaps regarding healthcare workers exposure to antineoplastic drugs review of literature north america versus europe
topic antineoplastic drugs
healthcare workers
knowledge gaps
occupational exposure
url http://www.sciencedirect.com/science/article/pii/S2093791114000432
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