Comparison of the effect of chamomile, Ginger and vitamin B6 on treatment of nausea and vomiting in pregnancy: a randomized clinical trial

Introduction: Nausea and vomiting is of the common complain during pregnancy. Herbal medicine is among the traditional treatments. This study was performed with aim to compare the effects of chamomile, Ginger and vitamin B6 on treatment of nausea and vomiting in pregnancy.  Methods: This randomized...

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Main Authors: Hamideh Pakniat, Mohammad Reza Memarzadeh, Nezal Azh, Maryam Mafi, Fatemeh Ranjkesh
Format: Article
Language:fas
Published: Mashhad University of Medical Sciences 2018-10-01
Series:Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
Subjects:
Online Access:https://ijogi.mums.ac.ir/article_11969_299c3757d211905c125a9757fec64a42.pdf
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author Hamideh Pakniat
Mohammad Reza Memarzadeh
Nezal Azh
Maryam Mafi
Fatemeh Ranjkesh
author_facet Hamideh Pakniat
Mohammad Reza Memarzadeh
Nezal Azh
Maryam Mafi
Fatemeh Ranjkesh
author_sort Hamideh Pakniat
collection DOAJ
description Introduction: Nausea and vomiting is of the common complain during pregnancy. Herbal medicine is among the traditional treatments. This study was performed with aim to compare the effects of chamomile, Ginger and vitamin B6 on treatment of nausea and vomiting in pregnancy.  Methods: This randomized clinical trial was performed on 105 pregnant women with gestational nausea and vomiting in Qazvin Health Centers in 2016-2017. The subjects were randomly assigned to three groups (intervention 1,2,3) (n=35 in each group). The intervention groups received oral capsule of chamomile, ginger and vitamin B6 for four days, three times a day. Rhodes index was used to assess nausea and vomiting before and 1 week after intervention. Data were analyzed by SPSS software (version 23) and t-test, Chi-square, Kruskal–Wallis and Wilcoxon. P<0.05 was considered statistically significant. Results: Before the intervention, no significant difference was observed between three groups in the mean of nausea, vomiting based on Rhodes index (p>0.05). Whereas, after the intervention, it showed significant decrease in three groups (P=0.001), but there was no significant difference between three groups in terms of decreased mean of nausea and vomiting (p>0.05). Conclusion: Chamomile, ginger and vitamin B6 are equally effective for decreasing nausea and vomiting in pregnancy and there is no significant superiority in therapeutic effects in any of the three drugs.
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spelling doaj.art-cb100eb164674ac7a26b7868a9d0654c2022-12-22T02:41:18ZfasMashhad University of Medical SciencesMajallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān1680-29932008-23632018-10-01218475410.22038/ijogi.2018.1196911969Comparison of the effect of chamomile, Ginger and vitamin B6 on treatment of nausea and vomiting in pregnancy: a randomized clinical trialHamideh Pakniat0Mohammad Reza Memarzadeh1Nezal Azh2Maryam Mafi3Fatemeh Ranjkesh4Assistant professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Qazvin University of Medical Science, Qazvin, Iran.PhD in Chemistry, Medicinal Plants Research Center, Barijessence Pharmaceutical Company, Kashan, Iran.Assistant professor, Department of Midwifery, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.M.Sc. in Biostatistics, School of Nursing and Midwifery, Qazvin University of Medical Sciences, Qazvin, Iran.Instructor, Department of Midwifery, School of Nursing and Midwifery, Qazvin University of Medical Sciences, Qazvin, Iran.Introduction: Nausea and vomiting is of the common complain during pregnancy. Herbal medicine is among the traditional treatments. This study was performed with aim to compare the effects of chamomile, Ginger and vitamin B6 on treatment of nausea and vomiting in pregnancy.  Methods: This randomized clinical trial was performed on 105 pregnant women with gestational nausea and vomiting in Qazvin Health Centers in 2016-2017. The subjects were randomly assigned to three groups (intervention 1,2,3) (n=35 in each group). The intervention groups received oral capsule of chamomile, ginger and vitamin B6 for four days, three times a day. Rhodes index was used to assess nausea and vomiting before and 1 week after intervention. Data were analyzed by SPSS software (version 23) and t-test, Chi-square, Kruskal–Wallis and Wilcoxon. P<0.05 was considered statistically significant. Results: Before the intervention, no significant difference was observed between three groups in the mean of nausea, vomiting based on Rhodes index (p>0.05). Whereas, after the intervention, it showed significant decrease in three groups (P=0.001), but there was no significant difference between three groups in terms of decreased mean of nausea and vomiting (p>0.05). Conclusion: Chamomile, ginger and vitamin B6 are equally effective for decreasing nausea and vomiting in pregnancy and there is no significant superiority in therapeutic effects in any of the three drugs.https://ijogi.mums.ac.ir/article_11969_299c3757d211905c125a9757fec64a42.pdfchamomilegestational nausea and vomitinggingerrhodes indexvitamin b6
spellingShingle Hamideh Pakniat
Mohammad Reza Memarzadeh
Nezal Azh
Maryam Mafi
Fatemeh Ranjkesh
Comparison of the effect of chamomile, Ginger and vitamin B6 on treatment of nausea and vomiting in pregnancy: a randomized clinical trial
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
chamomile
gestational nausea and vomiting
ginger
rhodes index
vitamin b6
title Comparison of the effect of chamomile, Ginger and vitamin B6 on treatment of nausea and vomiting in pregnancy: a randomized clinical trial
title_full Comparison of the effect of chamomile, Ginger and vitamin B6 on treatment of nausea and vomiting in pregnancy: a randomized clinical trial
title_fullStr Comparison of the effect of chamomile, Ginger and vitamin B6 on treatment of nausea and vomiting in pregnancy: a randomized clinical trial
title_full_unstemmed Comparison of the effect of chamomile, Ginger and vitamin B6 on treatment of nausea and vomiting in pregnancy: a randomized clinical trial
title_short Comparison of the effect of chamomile, Ginger and vitamin B6 on treatment of nausea and vomiting in pregnancy: a randomized clinical trial
title_sort comparison of the effect of chamomile ginger and vitamin b6 on treatment of nausea and vomiting in pregnancy a randomized clinical trial
topic chamomile
gestational nausea and vomiting
ginger
rhodes index
vitamin b6
url https://ijogi.mums.ac.ir/article_11969_299c3757d211905c125a9757fec64a42.pdf
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